Intro and Clinical Manifestations of Cancer Flashcards Preview

Oncology > Intro and Clinical Manifestations of Cancer > Flashcards

Flashcards in Intro and Clinical Manifestations of Cancer Deck (18):
1

early warning sign of colorectal cancer

blood in the stool

2

may be the only sign of bladder cancer

painless hematuria

3

Types of cancer that can cause pleural effusion

lung cancer or lymphoma

4

Type of cancer that can cause accumulation of peritoneal fluid

ovarian cancer

5

What causes anorexia and cachexia associated with cancer?

hypermetabolic state and abnormalities in fat/protein metabolism

6

Common manifestation of solid tumors except for breast cancer. More common in children and older adults. Weight lost from fat and skeletal muscle

Cancer anorexia-cachexia syndrome

7

Differences in liver mass with starvation vs cachexia

Starvation causes a decrease in liver mass but with cachexia liver mass increases

8

T/F Oral or parenteral nutritional supplementation reverses cachexia

false, it does not reverse cachexia

9

occurs in the neuromuscular junctions and muscles. Inability of the peripheral neuromuscular apparatus to perform a task in response to stimulus. Lack of ATP and build up of lactic acid

peripheral fatigue

10

Difficulty in initiating or maintaining voluntary activities. May be secondary to dysregulation of serotonin and proinflammatory cytokines

central fatigue

11

What are the mechanisms that malignancies can decrease RBC production by?

nutritonal, bone marrow failure, blunted EPO response, inflammatory cytokines decrease EPO production

12

Treatment of anemia

Epogen or transfusion

13

Collections of symptoms that result from substances produced by the tumor and occur remotely from the tumor itself

Paraneoplastic Syndromes

14

What cancers are most commonly associated with paraneoplastic syndromes

lung, breast, hematologic

15

What are the three most common paraneoplastic syndromes?

SIADH, Cushing syndrome, hypercalcemia

16

Paraneoplastic syndrome that can be associated with adenocarcinomas of the GI tract, lung, breast, ovaries, or hematologic cancers

acanthosis nigricans

17

Paraneoplastic syndrome that can be associated with small cell lung cancer

Lambert-Eaton Syndrome

18

Cancer that can cause myasthenia gravis

thymoma