Lymphomas Flashcards Preview

Oncology > Lymphomas > Flashcards

Flashcards in Lymphomas Deck (22):
1

tumor or cancer of blood cells or bone marrow

leukemia

2

cancer that starts in the lymph nodes or lymphatic system

lymphoma

3

produces abnormal white blood cells which inhibits the function of the immune system and platelet function-

leukemia

4

invades other organs by unnecessary and uncontrollable growth of lymphoid tissue

lymphoma

5

have symptoms typical of other cancers and may have no early telling symptoms, especially if chronic

leukemia

6

often present with signs of swollen lymph nodes in the neck, armpits or groin which are frequently painful

lymphoma

7

From what cells do red cells, basophils, neutrophils, monocytes, eosinophils, platelets originate?

myeloid cells

8

From what cells do T lymphocyts, B lymphocytes, NK cells originate

lymphocytic cells

9

Where are most lymphocytes located?

lymph nodes, spleen, bone marrow and lymphatic vessels

10

due to overexpression of BCL-2 (gene that blocks programmed cell death)

follicular lymphoma

11

What is the difference between the incidence of non-Hodgkins lymphoma and hodgkins lymphoma?

Hodgkin lymphomas have a bimodal distribution of occurrence whereas non-hodgkin lymphoma increases after age 40

12

Symptoms include: painless swelling in nodes, fever, night sweats, weight loss, fatigue, itchy skin

lymphoma

13

Subtypes of NHL

B and T cell

14

Common in patients with HIV

Burkitt's Lymphoma

15

Low Grade (slow growing, incurable) NHLs

Follicular, small lymphocytic, Waldenstrom’s

16

Intermediate Grade (rapid growing, potentially curable) NHLs

Diffuse large B cell, mantle cell, anaplastic large (T cell) NHL

17

High Grade (fastest growing, potentially curable) NHLs

Burkitt’s lymphoma, lymphoblastic lymphoma

18

different giant cells found with light microscopy in biopsies from individuals with Hodgkin's lymphoma. Usually derived from B lymphocytes

Reed-Sternberg cell

19

How are tumors of lymphoma categorized?

based on where the tumour is present (Ann Arbor system)

20

New biotherapy for treatment of NHL

antibody CD20 (Rituximab)

21

gives indication of degree of cellular breakdown

LDH levels

22

Standard therapy for many of the lymphomas

CHOP therapy