M&R Session 11- Drugs And The ANS Flashcards Preview

SOPHIE'S ESA 2 > M&R Session 11- Drugs And The ANS > Flashcards

Flashcards in M&R Session 11- Drugs And The ANS Deck (16)
1

Which branch of the ANS causes bronchoconstriction in asthma?

Parasympathetic

2

Which parasympathetic and sympathetic receptors are found in the airways?

M3 and B2

3

What is the preferred treatment of asthma?

Beta 2 adrenoceptor agonists

4

What are the other drugs that can be used to treat asthma? (3)

Xanthippe drugs
Muscarinic receptor antagonists
Steroids

5

How do Xanthippe drugs treat asthma?

They inhibit phosphodiesterase which breaks down cAMP, therefore meaning that smooth muscle can relax.

6

What is the clinical definition of hypertension?

>140/90 mmHg

7

What is the preferred treatment option for hypertension?

ACE inhibitors

8

Which adrenoceptors mediate vasoconstriction of vasculature?

Alpha 1

9

What are some of the signs and symptoms of thyrotoxicosis? (8)

Increased BMR
Heat intolerance
Warm, sweaty hands
Sweating
Weight loss
Increase appetite
Bulging eyes
Tachycardia

10

What is the main ANS drug used to treat thyrotoxicosis?

Beta 2 antagonists

11

What is another drug that is commonly used to treat thyrotoxicosis? What does it do?

Carbimazole
Prevents association of iodine into the thyroglobulin. Prevents iodination and therefore production of T3 and T4.

12

What is tachyphylaxis?

A reduced sensitivity due to excessive exposure to an agonist.

13

What is suprasensitivity due to?

Excessive antagonist exposure or deprived exposure to agonist.

14

What is an example of an endogenous opioid?

Endorphins

15

What do opioids act on?

Mu opioid receptors

16

What are 6 abnormalities in asthma?

Dyspnoea
Chest tightness
Chronic cough
Nocturnal cough
Wheezing
Symptoms precipitated by infection, allergens etc.

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