M&R Session 11- Drugs And The ANS Flashcards Preview

SOPHIE'S ESA 2 > M&R Session 11- Drugs And The ANS > Flashcards

Flashcards in M&R Session 11- Drugs And The ANS Deck (16)
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1
Q

Which branch of the ANS causes bronchoconstriction in asthma?

A

Parasympathetic

2
Q

Which parasympathetic and sympathetic receptors are found in the airways?

A

M3 and B2

3
Q

What is the preferred treatment of asthma?

A

Beta 2 adrenoceptor agonists

4
Q

What are the other drugs that can be used to treat asthma? (3)

A

Xanthippe drugs
Muscarinic receptor antagonists
Steroids

5
Q

How do Xanthippe drugs treat asthma?

A

They inhibit phosphodiesterase which breaks down cAMP, therefore meaning that smooth muscle can relax.

6
Q

What is the clinical definition of hypertension?

A

> 140/90 mmHg

7
Q

What is the preferred treatment option for hypertension?

A

ACE inhibitors

8
Q

Which adrenoceptors mediate vasoconstriction of vasculature?

A

Alpha 1

9
Q

What are some of the signs and symptoms of thyrotoxicosis? (8)

A
Increased BMR 
Heat intolerance 
Warm, sweaty hands
Sweating 
Weight loss 
Increase appetite 
Bulging eyes
Tachycardia
10
Q

What is the main ANS drug used to treat thyrotoxicosis?

A

Beta 2 antagonists

11
Q

What is another drug that is commonly used to treat thyrotoxicosis? What does it do?

A

Carbimazole

Prevents association of iodine into the thyroglobulin. Prevents iodination and therefore production of T3 and T4.

12
Q

What is tachyphylaxis?

A

A reduced sensitivity due to excessive exposure to an agonist.

13
Q

What is suprasensitivity due to?

A

Excessive antagonist exposure or deprived exposure to agonist.

14
Q

What is an example of an endogenous opioid?

A

Endorphins

15
Q

What do opioids act on?

A

Mu opioid receptors

16
Q

What are 6 abnormalities in asthma?

A
Dyspnoea
Chest tightness 
Chronic cough 
Nocturnal cough 
Wheezing 
Symptoms precipitated by infection, allergens etc.

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