Wednesday Wk 4 Mixed Flashcards

1
Q

ADH is synthesized in P__/S__ nuclei of hypothalamus
damage to PP causes transient DI as axonal __ and hypertrophy can allow release of hormone

AP releases hormones via __ eminence into Hypothalamic-hypophyseal portal vessels

only Leuks C/D/E4 and A__ can lead to bronchoconstriction
Leuks also promote mucosal __ and mucus secretion

I__ is antimuscarinic to block M3 receptors in asthma

A

paraventricular, supraoptic
regen

median

acetylcholine
edema

ipratropium

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2
Q

acute hepatitis post op usually due to exposure to __ inhaled anesthetics
ie H__ hepatitis and leads to __cellular damage
typical hepatitis sx w __ hepatic necrosis

NO is inhaled anesthetic that is antagonist of __ receptor

Succinylcholine/halogenated anesthetics can lead to M__

Nondepolarizing nicotinc receptor that competes w acetylcholine at end plate receptor V

A

halogenated
halothane
hepatocellular
centrilobular

NMDA

malignant hyperthermia

vecuronium

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3
Q

pt w Mono sx but missing sore throat and LAD likely has __
affects leuks of G__ lineage

protein digestion begins in __
must be broken to Di/tri/AA to be absorbed in __
E__ is responsible for activtating trypsin
Enteropeptidase def leads to probs w __/__ malabsorption

BA are conjugated to G/T to aid in digestion/absorption

Erythroblastosis fetalis and HDN occur w maternal anti-fetal __ type 2 HS Rxn
must be __ type to cross the placenta, thus it predominantly occurs in type __ mothers

A

CMV
granulocyte

stomach
SI
enteropeptidase
fat/protein

glycine, taurine

antibodies
IgG
O

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4
Q

PA due to CD4 t cells destroying parietal cells in stomach __/__
leads to loss of p__, round parietal cells in the upper glandular layer
normally secrete GA and __ to allow for VB12 absorption
just deeper is __ cells that secrete pepsinogen

BH4 is necessary to form S, T, and D

even pts w meningococcal vaccination need __ if exposed

A

body, fundus
pink
IF
chief

serotonin, tyrosine, dopamine

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5
Q

kidney develops from __ cord of urogenital ridge of intermediate mesoderm
Mesonephros system persists in males as __ ducts
Metanephric diverticulum aka __ bud forms collecting tubules, Major/minor calyces, and ureter
Metanephric __ forms glomerul, BS, P/D tubules and LoH

__ nucleus of hypothalamus regulates heat dissipation
__ nucleas mediates heat conservation

A__ nucleus secretes dopamine and GHRH and GnRH
P__ ncles releases ADH, CRH, oxytocin, TRH

S__ nucleus secretes ADH/oxytocin
S_ nucleus for circadian rhythm/pineal gland

A

nephrogenic
wolffian
ureteric
blastema

anterior
posterior

arcuate
paraventricular

supraoptic
suprachiasmatic

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6
Q

AP threshold is -__
after this, a rapid __ is seen

Macula has densely packed __ w no blood vessels
cone synapses on __ cell and then ganglioon cell
deposition of __ tissue leads to Dry MD
N__ leads to wet MD

PCA branches off __ artery
supplies CN __/__, thalamus, splenium, occipital lobe

Artery of percheron branches off __ to supply thalamus/dorsal midbrain
anterior __ artery is last branch off ICA to supply IC, optic tract, LGN, hippocampus

anti-IL 6 T__ can be used for GCA

A

55
action potential

cones
bipolar
fatty
neovascularization

basilar
3/4

PCA
choroidal

tocilizumab

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7
Q

Cocci is transmitted via __ inhalation
these turn into spherules containing __

main SE of TZD is fluid retention due to Na reabsorption in __

pt w loss of UE pain/temp, UE weakness/hyporeflexia, LE weakness and hyperreflexia has __
due to cystic dilaton that enlarges and damages V__/__ horn
VWC is decussation for 2nd order _ neurons
as it expands, can impact __ areas

RLS step of catecholamine synthesis is conversion of __ to DOPA via tyrosine hydroxylase
PNMT in AM is upregulated by __, thus if low, dec EPI release

A

spore
endospres

PCT

syringomyelia
VWC, anterior
lateral ST tract
other

tyrosine
cortisol

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8
Q

maximum intensity of AS murmur occurs as difference in __/__ pressures is greatest

Benzos/Barbs bind to __ binding sites of GABA to potentiate activity
use __ in acute panic attack

cerebellar vermis mediates axial/truncal __
connected to Medial descending motor systems ie A__ CS, reticulospinal, vestibulospnal, tectospinal tracts
can lead to nystagmus/vetigo if inferior vermis/__ node is involved

Limb dysmetria due to damage of cerebellar __
assc w lateral descending motor systems ie L__ CS tract and rubrospinal tract
may also see __ tremor

Resting tremor occurs w damage to __ and projections

A

LV/Aortic

allosteric
benzo

posutre
anterior
flocculonodular

hemispheres
lateral
intention

SN

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9
Q

__ necrosis after ischemic injury
tissue architecture is __ due to denatured lytic enzymes
cells lose __ and become eosinophilic
L__ infiltrate to digest debris

__ necrosis seen w bacteria infection w leuk recruitment or CNS infarct
necrotic cells digested by _ enzymes w viscous mass
presence of __ in fluid
see __ formation of infection
brain infarcts are filled w __

__ necrosis in panc, as lipase/other enzymes degrade Fats
releases FFA to bind __

__ necrosis w Tb infection/fungal
cheesy appearanc w __ material
forms a G__

A

coagulative
maintained
nucleus
leukocyte

liquefactive
lysosomal
pus
abscess
CSF

fatty
calcium

caseous
proteinaceous
granuloma

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10
Q

VB6 can be used to prevent stone formation in pt w __ stones due to decreasing its prodxn

focal mounding following percussion is myo__
specific for H__ due to slow reabsorption of Ca from SR
see __ muscle weakness and cramping

GC induced myopathy presents w proximal muscle weakness/atrophy without __
CK is __

Polymyalgia rheumatic CK is __
Statin myopathy CK is __

A

oxaluria

myoedema
hypothyroid
proximal

pain
normal
normal

elevated

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11
Q

RLS is assc w __/__

may be linked to __ def, maybe in SN

renal tubular acidosis is disoder of renal tubules w hyper__ normal AGAP MA

Distal (type 1)- urine pH __ 5.5
defect in __ cells ability to secrete proton
no new __ is generated, leading to MA
assc w hypo__ and inc risk for kidney stones
may be due to A__, analgesic nephropathy, congenital abnorms

A

CKD, DM
iron

chloremia
greater
a intercalated
HCO3
kalemia
amphotericin
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12
Q
Proximal RTA (type 2) ph is \_\_ 5.5
defect in PCT \_\_ reabsorption w inc excretion
urine is acidified by \_\_
assc w hypo\_\_ and inc risk for rickets
due to \_\_ syndrome and CA inhibs

Hyperkalemic RTA (type 4) urine pH is __ 5.5
hypo__ leads to hyperkalemia
dec __ in PCT so low NH4 excretion
anything that dec __ can cause, N__, H__ or aldosterone resistance

A
less
HCO3
a intercalated
kalemia
fanconi

less
aldosteronism
NH3
aldo, NSAIDs heparain

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