Wed Wk 6 Mixed 4 Flashcards
__ is anti-inflammatory cytokine
stops __ response and inhibits MHC class 2 expression
stops / and supports humoral immuity
TCA drugs inhbit NE/Serotonin reuptake and can lead to /
light microscopy of VZV shows __ inclusions in keratinocytes
Multinucleated __ w acantholysis
acantholysis w suprabasal blisters is __
eosinophilic cytoplasmic inclusions is -_
cytoplasmic vacuoles in keratinocytes/koilocytosis w hyperplasia is __
IL10
Th1
macros/DC
tremor/insomnia
intranuclear giant cells PV pox virus HPV
complete mole has __ in 1st trimester
uterus is __ w very high BHCG
leads to H and preeclampsia, hyperthyroid and __ cyst
see __ troph prolif w edematous villi (bunch of grapes)
no __ tissue
stains p57 __
Partial mole has vag bleeding and __ ab pain
uterus is _ w normal/high BHCG
some enlarged villi w __ proliferation
p57 is __
sarcoma butyroides is __ in young girls
see __ at bladder/vaginal mucosa
most important factors for hypogly in T1DM is excessive __ or inadeqaute __ or __
vaginal bleeding ENLARGED hyperemesis gravidarum theca lutein diffuse fetal negative
crampy normal focal positive rhabdomyosarcoma jelly like cyst
insulin, intake, exercise
GLUT4 can be translocated to cell membrane in __
pt on insulin is vulnerable to hypoglycemia as insulin __ to be released despite drop in glucose
exercise may change skin _ that aids in insulin uptake, exacerbating absorption
SNS activation typically leads to __
__ in NF1 cause visual loss
__ is hamartoma of eye iin NF1
also have __ abnorms and CNS tumors
gallstone ileus occurs due to __ fistula
look for air in __
charcot triad indicates __
muscle contraction
continues
perfusion
hyperglycemia
optic gliomas
lisch nodules
bone
cholecystoenteric fistula
biliary tree
ascending cholangitis
spinal cord ends at __ in adults
__ of spinal cord extends to form filum terminale, connecting conus medullaris to posterior __
dura ends at __ and fuses w filum terminale to form posterior coccyx
insert LP into / spaces
L4 VERTEBRAL BODY IS LOCATED at highest point of __
PSIS located at __ level
__ is invagination of sarcolemma in striated muscle
has L type Ca channels that allow for __ to rapidly propagate through the muscle fiber
ensures that Ca release from SR is __ in each muscle
uncoordinated contraction manifests as __
most common mode of HBV transmission is __
pia mater coccyx S2 L3/L4 or L4/L5 ILIAC CREST
S2
Transverse tubules
depolarization
uniform
syncronized contraction
sexual
Leg swelling, orthopnea is potential SE of D
Dry cough/exertional SOB is SE of B
Tarry stool/fatigue caused by chemo agents that affect __ dividing cells
usually due to __ agent
Ab pain/cholestasis and hepatitis are comps of __
AV fistula has __ mass w thrill on palpation w bruit
allow blood to go from arteries to veins, bypassing __ which is main source of resistance
thus, LV afterload is __
leads to high output __
communicating hydrocephalus has _ ventricles enlarged
due to disruptions of __
usually due to __ or hemorrhae
doxorubicin bleomycin rapidly alkylating mercaptopurine
palpable
arterioles
LOWERED
cardiac failure
all 4
arachnoid granulations
infection
in all types of placental injury, DIC IS MEDIATED BY __ to initiate coag cascade
vaginal bleeding, uterine tenderness, hematoma and fetal demise is placental __
assc w __
AFE assc w hypoTN and __
uterine rupture occurs w previous uterine __
see vaginal bleeding, acute ab pain, loss of fetal __
palpable fetal parts in __
__ breathing is cyclic pattern w inc/dec TV
seen in pt w __ and leads to hyperventilation w hypopcapnia
leads to __ during sleep when CO2 falls below certain level
w prolonged circulation bw lungs/brain, abnormal _ is sensed by alveoli/medullda
also seen in __ disease
deep labored breathing is _
OSA has normal _ even in non-apneic periods w minimal variation in TV
TISSUE FACTOR
abruption
HTN
cardiogenic shock
surgery
station
myometrium
Cheyne stokes CHF apnea PaCO2 CNS
kussmaul breathing
VENTILATION
Cholera is extremely __ sensitive
thus, if pt has reduced __ secretion, it is much easier for pt to become infected
pt w HCM has LVOT that is worse w __
thus avoid __ and __
_/__ and disopyramide are preferred
cAMP activates _ that can inhibit platelet aggregation
drugs that inc cAMP prevent plate __ change and granule release
thus, use C_ to inhibit phosphodiesterase and act as arterial vasodilator
Pt w PAD also needs / to reduce risk of thromboembolic events
hydatidiform mole due to overexpression of __ genes
becomes __ when villi invade myometrium (both invasive/complete have __ enlarged hydropic villi)
choriocarcinoma presents w vaginal bleeding and __
ACID
ACID SECRETION
volume depletion
VASODILATORS, DIURETICS
BB/NDCCB
PKA
shape
cilostozol
aspirin/clopidigrel
parental
invasive
diffusely
pulm manifestations
Avitaminosis A can lead to __ of epithelial lining of pancreatic exocrine ducts
normal levels are needed for __ of specialized epithelium such as mucus secreting columnar epithelium
infection of face enters cavernous sinus via _ facial vein system of S/I OV
sx include loss of all __
may affect CNV and its __ provision to face/corneal reflex
may have P/C due to impaired venous drainage
NPH due to \_\_ of arachnoid granulations \_\_ difficulties appear first, alongside UMN signs then \_\_ disturbs and urge incontinence look for \_\_ w/out sulci enlargement also for sx improvement upon \_\_
keratinizing squamous metaplasia
differentiation
valveless
EOM
sensory
proptosis, chemotosis
scarring
scarring
gait
cognitive
ventricular enlargement
CSF removal
Chancroid due to __
multiple, deep __ ulcers w gray/yellow base
gram stain shows __
Genital herpes have multinucleated giant cells w __ inclusions (Cowdry bodies)
__ due to Klebsiella granulomatis
extensive/progressive _ w out LAD/pain
see __ like tissue
deeply staining gram neg intracytoplasmic __ called donovan bodies
can lead to scarring/strictures w severe __ obstruction and lymphedema
Lymphogranuloma venereum due to C trach __
small, shallow painless __
large, painful Inguinal __/__
intracytoplasmic chlamydial _ in epithelial/leuks
may lead to F/lymph obstruction and fistulas
H ducreyi
painful
school of fish
intranuclear
Granuloma inguinale ulceration granulation cysts lymphatic
L1-L3 ulcers LAN/buboes inclusion bodies fibrosis
HCM due to systolic, anterior motion of __ toward IV septum
leads to __ and LVOT
see crescendo/decrescendo murmur located at /
craniopharyngioma is __ w solid areas
cysts filled w fluid composed of __ and cholesterol crystals
see dystrophic __ w strat squamous epithelium
scleroderma has upregulation of __ w progressive tissue fibrosis
leads to esophageal dysmotility w atrophy and __ replacement of muscularis in LES
leads to dilated LES w inc risk of /
__ is periodic, uncoordinated contractions of LES due to impaired __ innervation in myenteric plexus
MV
severe mitral regurgitation
LLSB/Apex
cystic
proteins
calcification
fibroblasts
fibrotic
GERD/strictures
Diffuse esophageal spasm
inhibitory
high levels of __ lead liver to produce APR
ESR places whole blood in tube that __ at bottom of tube over time
meausre of length of plasma on top after __
presence of APR like __ causes RBC to form rouleaux
this inc settling and __
larger VSD allow for __ of chamber pressures w dec LV spO2
bifid carotid pulse w brisk upstroke is __
fatigue/heart palpitations are common manifestations of __
anemia of chronic disease may have __
IL6 sediments 1hr FIBRINOGEN ESR
HCM
anemia
target cells
AE of ergosterol due to its ability to bind __
can have __ reactions
prevent w anti __/__
Nephrotoxicity due to dec in __, thus limit renal toxic drugs
monitor __ daily (K/Mg)
Anemia esp w hiv pt taking Z
pt w ovarian cancer presents w pelvic mass, A/P w appetite change, distension/bowel change
think __ ovarian cancer w anaplasia and stomal invasion, multiple papillary formations and psammoma bodies
CA-125 will be __
cholesterol injection site pyretics/histamines GFR Electrolytes ziduvidine
Epithelial: Serous cystadenoma is __ w Psammoma bodies
Mucinous: has P w mucin producing epithelial cells
Germ cell: Dysgerminoma more common in __
secretes /
histology is __
Yolk sac endodermal has high __ w __ resembling glomeruli
Sex cord: Granulosa secretes __ and __
See call exner bodies and __ nuclei
Sertoli leydig has high __ and looks like S/L cells
bilateral
pseudomyxoma peritonei
adolescents
BHCG, LDH
fried egg
AFP, schiller duval bodies
Estrogen/Inhibin
coffee bean
androgens
venous blood of legs goes from __ to deep veins to IVC
w high pressures, veins __ w incompetent valves
allows __ flow into superficial veins w high pressure
leads to ischemia and venous stasis __
extravasation of RBC leads to __ and brawny color
RF include obstruction via O/P, or chronic damage to valves DVT
Lymphedema is __ due to fibrosis/thickening of skin
superficial
dilate
retrogade
dermatitis
iron deposition
obesity, pregnancy
nonpitting
