Tues Wk 5 Mixed 2 Flashcards
pt w ms and spastic bladder has __ incontinence
due to __ lesion of SC preventing bladder from filling/relaxing as loss of inhib control has occurred
urodynamic studies show little/no __ and hypertonic blader
Flaccid bladder occurs w __ lesion
tetanospasmin heavy chain binds __ receptors on neuronal membranes
light chains stop release G/G from inhibitory interneurons
anaplastic cells lack __
loss of cell polarity w disrupted normal __ into sheets/islands
__ in sizes
nuclei are __ w clumped chromatin/nuceloli
lots of mitotic figures and giant __ cells
urge
UMN
residual urine
LMN
ganglioside
glycine/GABA
differentiation structure pleomorphic enlarged multinucleated
endocardial thickening/fibrosis w RHF indiates __ syndrome
serotonin stimulates __ growth and deposition
H/V are also secreted
pt w noncoronary atherosclerotic HD, DM and CKD are at high risk of __
similar to HTN/C/I/H
P450 Inducers
C/B/P/R/G/S/M/C
P450 inhibs
A/C/F/C/A/G/I/R
when psych sx are present DURING MD sx, diagnosis is __
schizoaffective occurs in __ of mood sx
carcinoid
fibroblast
histamine, VIP
CV events
cigarette smoking, immobility, hyperlipidemia
carbamazepine, barbs, phenytoin, rifapin, grisofulvin, St john wort, modafinil, cyclophosphamide
amiodarone, cimetidine, fluoro, clarithromycin, azole, grapefruit juice, ritonavir
MDD w psychotic features
ABSENCE
__ aka FNSD is sx/deficit of voluntary motor/sensory fxn incompatible w neuro cx/another disorder
sx must be __ like weakness, P, B, S
pt may be __
FSH forms dominant __ and release of estradiol from ovaries
this causes rise in __ and ovulation
failed ovulation occurs in __ dz
tx w M__ mimics FSH to develop follicle
__ has similar a subunit to LH, and causes ovulation
use IV __ insulin in DKA pt
can use __ in long term management, but not DKA due to __ depletion and erratic absorption
conversion do
neurologic, paralysis, blindness, seizure
indifferent
follicle LH PCOS menotropin HCG
regular
subcutaneously
volume
Rapid insulin is L, G, A do not \_\_ thus onset in 15 min and peak at 45-75 Regular onset is \_\_ min and peaks in 2-4hrs NPH works w/in \_\_ hrs w peak at 4-12 hrs Detemir is long acting w \_\_ bound to end works in \_\_ hrs and lasts up to 24hrs Glargine forms \_\_ in subq tissue does not have \_\_
Tx Pseudo w penicillins T/P cephalosporins C/C Aminoglycosides A/G/T Fluros C/L Monobactam A and carbanepem I/M
N gon undergoes antigenic variation via __ of pili proteins
lispro, glulisine, aspart polymerize 30 2 FA 2 microprecipitate peak
ticarcillin/pipercillin cetazidime, cefepime amikacin, gentamicin, tobramycin cipro, levo aztreonam imipenem, meropenem
recombination
G__ has trophozoite that is pathogenic and cyst that is infectious
pear shaped orgs w __ nuclei
sx include __ diarrhea, n, ab cramps and malabsorption
dz w stool __ for ova/parasites
biopsy shows villus __ and crypt hyperplasia
need __/__ to protect against this pathogen
CD8 necessary for C/T
retroperitoneal trauma leads to __ from blunt injury
think SAD PUCKER
intraperitoneal organism trauma leads to __
giardia lamblia 2 watery diarrhea microscopy atrophy IgA/CD4
Crypto, toxoplasma
hematoma
suprarenal, aorta/IVC, duodenum, pancreas, ureter/bladder, colon (A/D), kidney, esophagus, distal rectum
hemoperitoneum
AH produced by __ cells of ciliary body into pupil/anterior chamber
drains into __ angle through trabecular meshwork and schlemms canal w E/C veins
Glaucoma has high __ and dec peripheral vision
look for __ cup/disk ratio >.6
tx w T/nonselective BB to dec sec of AH by __
P__ promotes miosis by contracting iris sphincter thus inc trabecular outflow
also promotes __ contraction to inc convexity
A__ dec AH sec
Prostagland F2a L/T also dec intraocular pressure by inc outflow (uveoscleral pathway)
secondary lactose intolerance can result from I/I
damaged cells sloughed off, and replaced by cells w low __ conc
esp after __ infection
pes anserine burisitis occurs over __ knee
epithelial iridiocorneal episcleral/conjunctival IOP high timolol ciliary body pilocarpine ciliary muscle
Acetazolamide
latanoprost, travoprost
inflammation/infection
lactase
Giardia
anteromedial
use__ to determine RPF
filtered at __ and secreted at PT
filtration occurs at __ proportion and is not saturated
is secreted into tubular fluid in __ mediated process that can be saturated
above __, secretion plateaus and urine PAH is higher
not __ as it is secreted
__ is filtration + Secretion - reabsorption
FXS due to mutation in __ gene
see __ of joints w neuropsych sx
__ has acute/painless monocular visual loss
retina is __ w cherry red macula as blood comes from choroidal artery
due to T/E
DM pt may have blurry vision, __ spot/floater and dec peripheral vision
PAH glomerulus constant carrier transport maximum reabsorbed
excretion
FMR1
hyperlaxity
CRAO
pale
thrombosis, embolism
black
lymph drainage of scrotu m is to __ LN
lymph from glans penis/cutaneous posterior calf goes to __ LN
cerebellar ataxia, telangectasia, sinopulm infections is __ dz
inc risk of __ malignancy and CM/humoral immune probs
primarily __ deficient
AR mutation in __ gene responsible for DNA break repair
hypersensitive to chromosome __
lack of HLA Class 2 is _ syndrome
DiGeorge syndrome conotruncal abnorms due to impaired __ migration
involvement of __/__ pouches can lead to hypertelorism, short palpebral fissures and bifid uvula
Second branchial cleft is _ in utero
superficial inguinal
deep inguinal
Ataxia telangectasia heme IgA ATM breaks
bare lymphocyte
NCC
1/2
obliterated
Leprosy affects __/__ to degree depending on CMI
Tuberculoid leprosy has __ CMI response
see __ w hair loss and dec sensation
Lepromatous has __ CMI reponse w diffuse skin thickening, plaque hypopigmentation, leonine faces, blindness
Sarcoid can cause lesion to __ which dec dopamine and inc Prolactin
class 1 antiarrhthmics bind Na channel in __/__ state
use dependence means freq depolarizing tissues are more __ blocked
Class 1B has __ binding and thus prefers ischemic myocardium (low use dependence)
Class 1C has __ binding and thus use dependence
skin/nerves
intact
hypopigmentation
poor
AP
active/inactive
successfully
weakest
strongest
pleura protects __
no middle lobe on __ lung, plus superior lobe is displaced by cardiac shadow, thus __ is susceptible to penetration injury
N__ is required for release of virus/spread
A__ impairs uncoating/disassembly
plateau phase of opening of __ ca channels is unique to myocardium
L__ have high N:C ratio, condensed chromatin and prominent nucleoli
mature B cell leukemia has small, round __ B cells staining for CD19/CD5
rapidly progressive dementia w myoclonic jerks indicates __ dz
due to abnormal __ protein resistant to proteases
see spongiform vacuoles in __ and neurons of gray matter
LV
left
RV
neuraminidase
amantadine
L type
lymphoblasts
monomorphic
patches of demyelination in HIV pt is __
SSP has dementia, spasticity, seizures years after measles
pt w K/C Hb have high O2 affinity
thus, kidney stimulates E__ due to hypoxia
Renal failure, Fever, MHA, thrombocytopenia, AKI is __
FRIEDRICH ATAXIA INHERITANCE __
may have D__
UA stones are __ and not viewed on radiography
pt w __ have dec bicarb reabsorption in gut w resulting MA
kidneys excrete __ to reabsorb it and lower pH
this, along w dehydration, promotes __ crystallization
JC polyoma virus
Subacute sclerosing panencephalitis
Kempsey, Chesapeake
erythrocytosis
TTP-HUS
AR
diabetes
lucent
chronic diarrhea
H+
urate
