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Flashcards in Adenomyosis Deck (42)
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31

What is the only curative therapy for adenomyosis at present?

Hysterectomy

32

What are the more conservative approaches aimed at symptom control in adenomyosis?

- Analgesia
- Hormone therapy
- Non-hormone treatments

33

What analgesics are used in adenomyosis?

NSAIDs

34

What hormone therapies are available for the management of adenomyosis?

- Combined oral contraceptives
- Progestogens
- Gonadotrophin releasing hormone agonists
- Aromatase inhibitors

35

How can progesterones be administered in adenomyosis?

- Oral
- intrauterine system. e.g. Mirena

36

What is the purpose of hormonal therapy in adenomyosis?

Reduction of bleeding and cycle control

37

How do hormonal therapies work in adenomyosis?

Proposed that hormones reduce the proliferation of the ectopic endometrial cells, therefore reducing their mass and subsequently decreasing uterine size and volume of blood lost

38

What can temporarily induce the regression of adenomyosis?

Continuous combined oral contraceptive and high dose progestins, e.g. SC depot medroxyprogesterone

39

What are the non-hormonal treatments available in adenomyosis?

- Hysterectomy
- Uterine artery embolism
- Endometrial ablation and resection
- Laparoscopic excision
- MR-guided focused ultrasound

40

Is uterine embolism a long or short term management option for adenomyosis?

Short and medium

41

Who is uterine artery embolism a good option for in adenomyosis?

Women who wish to avoid hysterectomy and/or preserve their fertility

42

What is the aim of uterine artery embolism in adenomyosis?

Block blood supply to the adenomyosis, causing it to shrink