Flashcards in Adenomyosis Deck (42)
What is the only curative therapy for adenomyosis at present?
What are the more conservative approaches aimed at symptom control in adenomyosis?
- Hormone therapy
- Non-hormone treatments
What analgesics are used in adenomyosis?
What hormone therapies are available for the management of adenomyosis?
- Combined oral contraceptives
- Gonadotrophin releasing hormone agonists
- Aromatase inhibitors
How can progesterones be administered in adenomyosis?
- intrauterine system. e.g. Mirena
What is the purpose of hormonal therapy in adenomyosis?
Reduction of bleeding and cycle control
How do hormonal therapies work in adenomyosis?
Proposed that hormones reduce the proliferation of the ectopic endometrial cells, therefore reducing their mass and subsequently decreasing uterine size and volume of blood lost
What can temporarily induce the regression of adenomyosis?
Continuous combined oral contraceptive and high dose progestins, e.g. SC depot medroxyprogesterone
What are the non-hormonal treatments available in adenomyosis?
- Uterine artery embolism
- Endometrial ablation and resection
- Laparoscopic excision
- MR-guided focused ultrasound
Is uterine embolism a long or short term management option for adenomyosis?
Short and medium
Who is uterine artery embolism a good option for in adenomyosis?
Women who wish to avoid hysterectomy and/or preserve their fertility