Genital Herpes Flashcards Preview

B - Gynaecology > Genital Herpes > Flashcards

Flashcards in Genital Herpes Deck (44)
1

What is genital herpes?

A sexually transmitted infection caused by the herpes simplex virus

2

How is genital herpes transmitted?

By skin-to-skin contact through vagina, anal or oral sex

3

How long can genital herpes infection take to show?

Once infected people may be asymptomatic for a long period before the first flare up

4

What happens to the virus after resolution of primary genital herpes infection?

Can lie dormant until it returns in later life causing recurrent outbreaks

5

How many cases of genital herpes are there each year in England?

31,000

6

What % of newly diagnosed STI's are genital herpes?

7%

7

What is happening to the rate of genital herpes infections?

Rising

8

What % of genital herpes occurs in people aged 15-24?

42%

9

Why are diagnostic rates and prevalence of genital herpes thought to be underestimated?

Many people don't know they are infected

10

What are the 2 main types of herpes simplex virus?

HSV-1 and HSV-2

11

What can be caused by HSV-1?

- Cold sores
- Genital sores

12

What can be caused by HSV-2?

Genital herpes

13

What is the consequence of HSV-1 and 2 causing oral and genital herpes?

It can be spread via oral sex with a cold sore sufferer

14

How does HSV enter the body?

Via small cracks in the skin or through mucous membranes of the mouth, vagina, rectum, urethra or under the foreskin

15

Where does HSV travel after infecting the surface?

The nearest nerve ganglion and remains there

16

What does travelling to the nerve ganglion allow HSV to do?

Remain dormant for a long time

17

Why does remaining in the nerve ganglion allow the HSV to remain dormant?

It cannot be reached by the immune system

18

How does the HSV become reactivated?

It travels back down the nerve onto the surface of the genitals to cause a symptomatic outbreak

19

Can HSV be spread when asymptomatic?

Yes

20

How can HSV be spread when asymptomatic?

Through asymptomatic shedding

21

What are the risk factors for genital herpes?

- Multiple sexual partners
- Previous history of STIs
- Early age of first sexual intercourse
- Unprotected sexual encounters
- MSM (and female partners of MSM)
- Female gender
- HIV infection

22

What are the symptoms of primary genital herpes infection?

- Small, red, painful blisters around genitals
- Vaginal or penile discharge
- Flu-like symptoms, fever and myalgia
- Itchy genitals

23

What can happen to primary genital herpes blisters?

Can form open sores

24

Where do genital herpes sores present in men?

- Penis
- Anus
- Buttocks
- Thighs

25

Where do genital herpes sores present in women?

- Vulva
- Clitoris
- Buttocks
- Anus

26

How long does it take for primary genital herpes lesions to crust and heal?

20 days

27

How do secondary genital herpes infections differ from primary infection?

Often shorter and less severe and increasingly so with each infection

28

Why are secondary genital herpes outbreaks shorter and less severe?

Production of antibodies allows for a more effective response

29

What are the symptoms of recurrent outbreaks of genital herpes?

- Burning and itching
- Painful red blisters

30

What are cold sores?

Painful red blisters around the mouth and nose that last 7-10 days

31

What causes cold sores?

Mainly HSV-1 but also HSV-2

32

How can cold sores spread to cause genital herpes?

If oral sex received from someone with a cold sore

33

What are the differentials for genital herpes?

- Vulvovaginal candidiasis
- Other STI's
- Scabies
- Psoriasis
- Dermatitis
- Reiter's syndrome
- Genital malignancy
- Herpes zoster

34

Where is genital herpes best diagnosed?

During primary infection at a GUM clinic or GP surgery

35

What history should be taken to help diagnose genital herpes?

- Sexual partners
- History of cold sores or similar symptoms
- Any other STI's

36

What investigation should be taken if patient presents with open genital herpes sores?

Swabs for testing presence of HSV and PCR to differentiate types 1 and 2

37

Is a negative swab a definite exclusion of genital herpes?

No

38

How can symptom duration of primary infection and recurrence of genital herpes be treated?

Over the counter medications

39

What mediation is effective at reducing the number and size of primary genital herpes lesions?

Aciclovir

40

What should a patient be offered after clearance of primary genital herpes infection?

Full sexual health screen and advice about preventing transmission

41

What advice should be given to patients with genital herpes?

Avoid all sexual contact during outbreak and disclose infection to all recent and current sexual partners

42

What can be used to reduce the discomfort of a genital herpes infection?

- OTC painkillers
- Petroleum jelly
- Ice pack

43

What is recommended if episodes of genital herpes are regular?

Take aciclovir as soon as symptoms start

44

What is recommended if episodes of genital herpes are very frequent?

Daily dose of aciclovir to suppress outbreaks