Flashcards in Drugs Deck (26)
Which category of drug competitively antagonizes acetylcholine (vagal tone)?
What do anticholinergics inhibit and how do they do so?
- By decreasing vagal tone.
What might anticholinergics cause?
What do anticholinergics reduce?
What effect do anticholinergics have on gastric pH?
Increase gastric pH
What effect do anticholinergics have on gastrointestinal motility?
Decrease gastrointestinal motility
What are two common side effects of anticholinergics?
Which two anticholinergics may produce drowsiness?
Which anticholinergic does not cross the blood-brain barrier or placental barriers?
Which anticholinergic may slow the heart rate (bradycardia) temporarily after IV administration?
What type of cardiac arrhythmias can atropine or glycopyrrolate cause if given IV?
What else can atropine given IV cause?
- First and second degree AV blocks before sinus tachycardia.
- Ventricular arrhythmias
What might atropine cause in dogs & cats?
What might anticholinergics cause in horses?
What do phenothiazines cause?
Calming and muscle relaxation.
What are 3 effects phenothiazines have?
What do phenothiazines do to analgesics?
Where are phenothiazines metabolized?
What is the normal DOA for phenothiazines?
Effects can be seen for up to how long?
- 4 to 8 hours
- Up to 48 hours
Can phenothiazines cause hypertension or hypotension?
Can phenothiazines cause hyperthermia or hypothermia?
What do phenothiazines inhibit?
T/F: Phenothiazines are analgesic.
False - They are not analgesic.
What is the concern with using phenothiazines in an epileptic patient?
They may lower seizure threshold in animals with epilepsy.
What are 2 side effects seen with excessive doses of phenothiazines or butyrophenones?
Which species is particularly susceptible?
- Apparent involuntary musculoskeletal effects and hallucinatory activity.
What side effect with phenothiazines can be seen in Boxers?