Dyspepsia + Peptic Ulcer Disease Flashcards Preview

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Flashcards in Dyspepsia + Peptic Ulcer Disease Deck (13)
1

What are the 2 groups of causes of dyspepsia? Which is most common?

Organic causes
Functional dyspepsia (most common)

2

Give examples of organic causes of dyspepsia

Peptic ulcer disease
Drugs (NSAIDs)
Gastric cancer

3

What is meant by functional dyspepsia?

Dyspepsia symptoms with no evidence of structural disease, i.e. not due to ulcers or H. pylori
Usually assoc. with functional gut disorders

4

Is dyspepsia the same as GORD?

Nope
Dyspepsia is a range of symptoms with multiple causes; GORD is due to reflux of acid from the stomach

5

Outline the Rome III criteria for functional dyspepsia

Feeling of fullness or epigastric pain/burning
AND no evidence of structural disease
For past 3 months, with symptom onset 6 months before diagnosis

6

What is the commonest organic cause of dyspepsia?

Peptic ulcer disease

7

When does pain related to peptic ulcer disease often come on?

At night after eating
Duodenal ulcers aggravated by stomach emptying

8

What are the two most common causes of peptic ulcer disease?

H. pylori
Drugs (NSAIDs)

9

Where are peptic ulcers more common - the oesophagus, stomach or duodenum?

Duodenum
Then stomach; don't really occur in oesophagus

10

What tests are done to diagnose H. pylori infection?

Stool antigen test
Urease breath test
Serology (IgA antibodies)

11

Which drugs are used to treat peptic ulcer disease?

Antacids (Gaviscon)
H2 antagonists (ranitidine)
PPI (omeprazole)

12

Outline triple therapy for H. pylori eradication

Omeprazole + amoxicillin + clarithromycin
Omeprazole + metronidazole + clarithromycin

13

If a patient is still symptomatic after H. pylori triple therapy, a retest to detect the organism is done. How long must a PPI be stopped before retest is done?

2 weeks