Irritable Bowel Syndrome Flashcards Preview

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Flashcards in Irritable Bowel Syndrome Deck (12)
1

Define irritable bowel syndrome as per Rome III criteria

Recurrent abdo pain for 3 days/month for 3 months
+ at least 2 of
Improvement with defecation
Change in stool frequency
Change in stool appearance

2

Is IBS an acute or chronic presentation?

Chronic - has been going on for months

3

Who is more commonly affected by IBS - males or females?

Females 2:1 Males
Oestrogen-driven disease

4

The aetiology of IBS is unclear, but what is the most common proposed mechanism seen in 2/3 of patients?

Visceral hypersensitivity

5

List some symptoms of IBS

Bloating
Abdo pain/discomfort
Increased frequency of toilet visits
Mucus stool
Incomplete emptying

6

What are the most common trigger factors of IBS?

Diet (bread, low-fibre)
Infection
Menstruation
Drugs (opiates e.g. codeine)
Psychological factors

7

What are some alarm features of IBS symptoms that warrant deeper investigation?

Age > 50
More recent onset
Woken up from sleep needing toilet
Rectal bleeding
Weight loss
Anaemia
Family history of CRC

8

List some general investigations done for IBS

FBC
CRP
Antibody test for coeliac disease
Lower GI test if age > 50

9

What is the initial, and often most effective, management of IBS?

Improve diet - reduce fibre and meal times
Stop opiates and analgesia

10

Name an anti-spasmodic drug that could be used for IBS

Mebeverine
Hyoscine

11

Name an anti-diarrhoeal agent

Loperamide

12

Name an anti-depressant agent that may be used for IBS

Amitryptiline