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Flashcards in Gastric Disease Deck (20)
1

Gives causes of acute gastritis

Chemical irritation
Trauma
Burns

2

What are the 3 main causes of chronic gastritis?

Chemical insult
Bacterial (H. pylori)
Autoimmune disease

3

In terms of aetiology of chronic gastritis, chemical insult rarer than bacterial infection which is rarer than autoimmune disease. True/False?

False
Other way around! Chemical insult is most common, followed by bacterial, then autoimmunity

4

What happens in autoimmune gastritis?

Antibodies destroy parietal cells + intrinsic factor
Can lead to pernicious anaemia

5

What is the most common bacteria that causes bacterial gastritis?

H. pylori

6

Where does H. pylori like to reside?

Between the epithelial cell surface + mucosal barrier, where it can cause inflammation

7

Which chemicals are the most common causes of chemical gastritis?

NSAIDs
Alcohol
Bile reflux

8

How does chemical insult affect the stomach?

Dissolves + destroys lipid bilayer, causing inflammation, hyperplasia and ulcers

9

Define "peptic ulceration"

Breach of the GI mucosa by acid/pepsin attack

10

Where are common sites for peptic ulcers?

Duodenum (1st part)
Stomach
Gastro-oesophageal junction

11

Name some benign gastric tumours

Mainly polyps - hyperplastic polyps or fundic gland polyps

12

Name some malignant gastric tumours

Adenocarcinoma
Lymphomas
Gastrointestinal stromal tumours (GISTs)

13

Where do adenocarcinomas of the stomach tend to develop?

Proximally (GO junction, cardia)

14

Pernicious anaemia is a premalignant condition. True/False?

True

15

Intestinal type gastric adenocarcinoma has better prognosis than diffuse type. True/False?

True

16

From which tissue is gastric lymphoma derived?

MALT (mucosal-associated lymphoid tissue)

17

What is gastroparesis?

Delayed gastric emptying that is NOT due to obstruction

18

Give examples of symptoms of gastroparesis

Feeling of fullness, bloating
Nausea, vomiting
Weight loss
Abdominal pain

19

What investigations are done for gastric cancer?

Endoscopy
Barium meal
CT scan

20

In surgery for gastric cancer, when is a partial and total gastrectomy done?

Total gastrectomy for proximal lesions
Partial gastrectomy for distal lesions