Flashcards in Gastric Disease Deck (20)
Gives causes of acute gastritis
What are the 3 main causes of chronic gastritis?
Bacterial (H. pylori)
In terms of aetiology of chronic gastritis, chemical insult rarer than bacterial infection which is rarer than autoimmune disease. True/False?
Other way around! Chemical insult is most common, followed by bacterial, then autoimmunity
What happens in autoimmune gastritis?
Antibodies destroy parietal cells + intrinsic factor
Can lead to pernicious anaemia
What is the most common bacteria that causes bacterial gastritis?
Where does H. pylori like to reside?
Between the epithelial cell surface + mucosal barrier, where it can cause inflammation
Which chemicals are the most common causes of chemical gastritis?
How does chemical insult affect the stomach?
Dissolves + destroys lipid bilayer, causing inflammation, hyperplasia and ulcers
Define "peptic ulceration"
Breach of the GI mucosa by acid/pepsin attack
Where are common sites for peptic ulcers?
Duodenum (1st part)
Name some benign gastric tumours
Mainly polyps - hyperplastic polyps or fundic gland polyps
Name some malignant gastric tumours
Gastrointestinal stromal tumours (GISTs)
Where do adenocarcinomas of the stomach tend to develop?
Proximally (GO junction, cardia)
Pernicious anaemia is a premalignant condition. True/False?
Intestinal type gastric adenocarcinoma has better prognosis than diffuse type. True/False?
From which tissue is gastric lymphoma derived?
MALT (mucosal-associated lymphoid tissue)
What is gastroparesis?
Delayed gastric emptying that is NOT due to obstruction
Give examples of symptoms of gastroparesis
Feeling of fullness, bloating
What investigations are done for gastric cancer?