Flashcards in Borrelia Deck (25)
endemic relapsing fever is caused by?
vector of endemic relapsing fever
genus Ornithodorus (ticks)
False abt Borrelia recurrentis
A. can be cultured in fluid media
B. slow multip in chick embryos
C. passed from gen to gen in some ticks
D. stain readily with bacteriological dyes
false about antigenic structure of B.recurrentis
A. remain the same throughout course of single infection
B. permit survival of only antigenically distinct variants
C. act as selective factor
D. none of the 3
Which is not a fatal manifestation of the presence of B.recurrentis?
A. hemorrhagic lesions in kidney and GIT
B. spirochetes in liver and spleen
C. over heating of the heart
D. spirochetes in brain and spinal fluid
Before B.recurrentis enters the bloodstream, what part of the body does it infect?
false about febrile stage of B.recurrentis pathogenesis:
A. organism is absent
B. antibodies vs spirochetes are present
C. attack is terminated by agglutinating and lytic effects
D. relapse may still occur
organism is present; sa afebrile stage siya wala.
in thick/thin blood smears, what smear is used?
C. both A& B
D. none of the choices
Animal inoculation (white mice): used for diagnosis of relapsing fever. How is the bacteria inoculated?
Which is not a way for a tick to transmit B.recurrentis?
B. being crushed
C. both are ways
D. both are not ways
infected humans with lice --> lice becomes infected by ___
Vaccination is a method commonly used to prevent relapsing fever. T or F
no vaccine is available
What disease is caused by Borrelia bugdorferi?
Lyme disease's causative agent is transmitted by bite of a small __ tick
T or F: B.burgdorferi stains readily with acid dye but not with aniline dye
it can readily be stained by both dyes
What structure makes B.burgdorferi highly motile?
complex liquid medium used to culture B.burgdorferi
What helps B.burgdorferi live in very diff ticks and mammalian hosts?
large number of sequences of lipoproteins
In the course of pathogenesis, B.burgdorferi adheres to ___ on host cells. c/o ___
borrelial GAG receptor
In what stage does erythema chronicum migrans happen?
A. stage 1
B. stage 2
C. stage 3
D. all 3 stages
Which is false about B.burgdorferi diagnosis?
A. blood is used for seroloical tests
B. CSF is the best sample
C. culture takes 6-8 weeks
D. molecular probes(PCR) have 85% sensitivity, but lower sensitivity @ synovial fluid samples
Western blot is a technique used to confirm results by other tests. It usually utilizes the ____ with the bacteria's proteins
size of the antibody reactions
In electrophoresis, the antigens of B.burgdorferi are separated and transferred to a ___ + reacted with patient serum
Which is false?
A. immunologic response develops slowly
B. early antimicrobial treatment increases antibody response
C. both are true
D. both are false