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PH 152 > Rickettsiae > Flashcards

Rickettsiae Flashcards

1
Q

causative agent of typhus fever

A

Rickettsia prowasekii

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2
Q

during World War I, this diagnostic agglutination test for typhus was developed

A

Weil-Felix reaction

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3
Q

false about Rickettsiae:

a. anaerobic
b. Gram (-) but Gram stain poorly
c. contains LPS and peptidoglycan
d. all of the above are true

A

A

aerobic sila

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4
Q

false about Rickettsiae:

a. Obligate intarcellular parasites (except for Rochalimaea)
b. require growth cofactors (e.g. acetyl-CoA, NAD, ATP) provided by the cell
c. grow on artificial media & on cytoplasm of eukaryotic cells
d. all of the above are true

A

C

They do not grow on artificial media

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5
Q

After transmission, Rickettsia multiplies in endothelial cells of ___

A

capillaries

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6
Q 
Which does not happen in pathogenesis of Rickettsiae?
A. local hypersensitivity
B. regional lymphadenopathy
C. intracellular multiplication
D. none of the above
A

D

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7
Q 
Rickettsia may be transmitted through these invertebrates (to humans), except
A. fleas
B. mites 
C. ticks
D. spiders
A

D

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8
Q

T or F

Transmission of Rickettsiae in arthropods is transovarial.

A

T

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9
Q

Another name for epidemic recrudesent typhus

A

Brill-Zinsser typhus

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10
Q 
Causative agent of Boutonneuse typhus
A. R.canari
B. R. akari
C. R. tsutsugamushi
D. All of the 3
A

A

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11
Q 
Causative agent of Rickettsial pox
A. R.canari
B. R. akari
C. R. tsutsugamushi
D. All of the 3
A

B

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12
Q 
Causative agent of Scrub typhus
A. R.canari
B. R. akari
C. R. tsutsugamushi
D. All of the 3
A

C

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13
Q

Enumerate the scientific names of the vectors of epidemic typhus

A

Pediculus humanus corporis

Pediculus humanus capitis

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14
Q

One of the symptoms of epidemic typhus is maccular rash after 4-7 days. True or false?

A

true

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15
Q

This type of typhus occurs after the person recovered from epidemic typhus and reactivation of R.prowazekii which remained latent for many years

A

Brill-Zinsser typhus

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16
Q

another name for endemic typhus

A

murine typhus

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17
Q

causative agent of endemic typhus

A

R. typhi

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18
Q

vector of endemic typhus

A

Xenopsylla cheopis

19
Q

Rocky Mountain Spotted fever is caused by __

A

R. rickettsii

20
Q 
False about rash @ Rocky Mountain spotted fever
A. spread is from trunk to extremites
B. sharply defined maculopapular
C. both are true
D. both are false
A

A

baliktad

21
Q

benign febrile illness with vesicular rash resembling chicken pox

A

rickettsial pox

22
Q

vector of Rickettsial pox

A

Liponyssoides sanguineus

23
Q

reservoir host of Rickettsial pox

A

Mus musculus

24
Q

Species formerly under Rochalimaea genus are now under ___ genus

A

Bartonella

25
Q 
Some Rickettsia species may cause eschar. Which of the ff bacteria may also cause eschar:
A. Bacillus anthracis
B. Yersinia pestis
C. Vibrio cholerae
D. Streptococcus agalactiae
A

A

26
Q

gold standard in diagnosing Rickettsial infection

A

culture and isolation

27
Q

PCR may be used to confirm diagnosis of ___ when infection

A

ehrlichiosis

28
Q 
In Weil-Felix test, what strains are used to find rickettsial antibodies in patient serum?
A. non-motile Shigella strains
B. motile Salmonella strains
C. non-motile Proteus strains
D. motile Enterobacter strains
A

C

29
Q

Most common strain used in Weil-Felix test

A

OX 19

30
Q

In Weil-Felix test, the doctor can diagnose endemic/epidemic typhus if
A. strong agglutination with OX19 and OX2
B. strong agglutination with OX 19
C. strong agglutination with OX K
D. strong agglutination with OX 2

A

B

31
Q

primary reservoir of R.ricketsii

A

ticks

32
Q

mode of transmission of R.prowazekii

A

breaks in skin c/o body louse

33
Q

mode of transmission of R.typhi

A

infected flea inoculates via skin break

34
Q

Coxiella burnetii has two modes of transmission. Enumerate.

A

airborne particles from contaminated sources

+ ingestion of unpasteurized milk

35
Q

How is Ehrlichia chaffeensis transmitted?

A

break in skin via infected tick

36
Q

mode of transmission of R.akari

A

mites

37
Q

mode of transmission of R.canari

A

ticks

38
Q

T or F. Squirrels are reservoir hosts of R.prowazekii

A

T

39
Q 
Which is not a  reservoir host of Coxiella burnetii?
A. cattle
B. sheep
C. goats
D. humans
A

D

40
Q

Coxiella burnetii causes __

A

Q fever

41
Q

What is the etiologic agent of trench fever?

A

Rochalimaea quintana
OR
Bartonella quintana

42
Q

What is pellosis?

A

pathological entity characterized by gross appearance of multiple cyst-like, blood-filled cavities within parenchymatous organs

43
Q

What is the etiologic agent of bacillary pellosis?

A

Rochalimaea henselae
OR
Bartonella henselae

PH 152 (47 decks)

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