Flashcards in Neisseria Deck (20)
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Structural elements of N. meningitidis and N. gonorrhoeae are same except that one of then has a polysaccharide capsule external to the cell wall. Which one?
N. meningitidis
1
N. meningitidis and N. gonorrhoeae Which one is more fastidious?
N. gonorrhoeae
2
N. meningitidis serogroup __ causes widespread epidemics
A
3
Serogroups of N.meningitidis are based on
A. Outer membrane proteins
B. Polysaccharide capsule
C. Both of the above
D. None of the above
Serogroups are based on OMP’s and polysaccharide capsule
Answer: C
4
False about N.meningitidis
A.Transmission by inhalation of aerosolized respiratory droplets
B. Infection is highest among infants
C. zoonotic disease happens more often because of this bacteria
D. None of those mentioned
C
Human: only natural host
5
Which is not a virulence factor of N.meningitidis?
A. Capsule
B. Lipooligosaccharide
C. IgE protease
D. Outer membrane proteins
C
IgA dapat
6
A.enters epithelium through membrane-bound vesicles
B.Pili attaches to CD46 protein of epithelial cells
C.damages cell by releasing endotoxin, travels through cell
D.exits cell to bloodstream
E. Bacteremia and invasion of CNS
Arrange steps in pathogenesis of N.meningitidis
B A C D E
7
N.meningitidis grows in the ff except
A. Blood Agar Plate
B. Chocolate Agar
C. Bordet - Gengou Medium
D. None of the above
C
8
First choice treatment drug for N.meningitidis
Penicillin
9
Prophylaxis antibiotics for N.meningitidis
Rifampin, Ciprofloxacin
10
Transmission of N.gonorrheae
Sexually transmitted
11
Neisseria stick to mucous secretions and non-ciliated cells by their __ and __
Neisseria stick to mucous secretions and non-ciliated cells by their pili and Opa proteins
12
___ of pili, Opa proteins and LOS enables gonococci to escape immune surveillance
Antigenic variation of pili, Opa proteins and LOS enables gonococci to escape immune surveillance
13
False about N.gonorrheae
A.Anaerobic
B.Converts glucose to acetic acid
C.Capnophilic-
D.Require iron and nitrogen for growth -
A
aerobic dapat
14
N.gonorrheae is said to be auxotrophic. What does this mean?
require one or more substances for growth
15
Pathogenesis of N.gonorrheae: fill in the blanks
Initial attachment mediated by ___ Tighter attachment mediated by ___
Pili
Opa proteins
16
__ trigger signaling cascade to induce phagocytosis of bacterial cell
A. Pili
B. Lipopolysaccharide
C. Opa proteins
C
17
Ingestion and transport through epithelium is ___ to that of meningococci
A. Similar
B. Different
C. Varied
A
18
What is parasite-mediated endocytosis?
Microbe tells microvilli via signals to phagocytose the said bacteria
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