Flashcards in Respiratory Viruses Deck (61)
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1
family of influenza virus
Orthomyxoviridae
2
Which influenza type is zoonotic?
A. A
B. B
C. C
A
3
Which is true?
A. All have 2 surface glycoproteins.
B. All have segmented genome.
C. All cause human epidemics & pandemics.
D. All have matrix proteins.
B
Type C has 1 surface glycoprotein.
Human epidemics c/o Types A & B
Type A - matrix proteins + pandemic
4
Which specific influenza virus was termed "Spanish flu" in 1918-19?
A(H1N1)
5
Which specific influenza virus was termed "Asian flu" in 1957-58?
A(H2N2)
6
Which specific influenza virus was termed "Hong Kong flu" in 1968-69?
A(H3N2)
7
main mode of transmission of influenza
Aerosol
8
enumerate the protein spikes in influenzae
hemagglutinin or "H" spike
neuraminidase or "N" spike
9
posttransitional cleavage occurs in:
A. hemagglutinin or "H" spike
B. neuraminidase or "N" spike
C. both
D. neither
A
10
facilitates release of virion
A. hemagglutinin or "H" spike
B. neuraminidase or "N" spike
C. both
D. neither
B
11
promotes fusion
A. hemagglutinin or "H" spike
B. neuraminidase or "N" spike
C. both
D. neither
A
12
prevents aggregation of virus
A. hemagglutinin or "H" spike
B. neuraminidase or "N" spike
C. both
D. neither
B
13
cleaves sialic acid residues of mucus
A. hemagglutinin or "H" spike
B. neuraminidase or "N" spike
C. both
D. neither
b
14
binds to receptor with sialic acid
A. hemagglutinin or "H" spike
B. neuraminidase or "N" spike
C. both
D. neither
A
15
Minor mutations in the hemagglutinin antigen
• Makes prior immunity less effective and ensures that
enough susceptible people are available for the
survival of the virus
identify
antigenic drift
16
Occur when two separate strains of influenza infect
the same cell simultaneously
antigenic shift
17
may cause pandemics
A. antigenic shift
B. antigenic drift
C. both
D. neighter
A
18
Which is not a reason for Type B's "non-pandemicity"?
A.There is no known animal reservoir.
B. Antigenic shifts only
C. both
D. neighter
B
drift, not shift
shift-->pandemic
19
Sequence the pathogenesis of influenza:
A. secondary bacterial infection
B. impairment of ciliary clearance
C. inflammation and irritation of respi tract
D. virus binds to ciliated columnar cells
E. shedding of ciliated columnar cells
D E B C A
20
Croup is a __ complication of influenza in young children.
A. neurologic
B. cardiac
C. gastrointestinal
D. pulmonary
D
21
Reye's syndrome is a complication of influenza @ __
A. liver
B. CNS
C. lungs
D. A and B
E. B and C
D
22
Guillan-Barre syndrome is a complication of influenza @ __
A. CNS
B. PNS
C. Both
D. Neither
B
23
antiviral drug that is as effective as vaccine in preventing influenza
amantadine
24
zanamivir and oseltamivir inhibit __
sialidase
25
rimantadine and amantadine work only for type __
A. A
B. B
C. C
A
26
enumerate components of flu vaccine
A(H1N1)
A(H3N2)
B
27
T or F
The yearly vaccine is the activated type.
F
inactivated dapat
28
Why is the interferon important?
o Puts the infected cell into an antiviral state to prevent
the attachment or entry of the virus
29
Which is false?
A. IgG and IgA that were produced due to a specific strain will only be protective for that strain only
B. NA antibodies more important because they can neutralize
C. both
D. neither
B
HA dapat
30
