Flashcards in Systemic Mycoses Deck (40)
Etiologic agents of systemic mycoses are ___ fungi
reproductive pattern of molds
possible causative agents of Valley Fever
Coccidioides immitis and Coccidioides posadasii
gross morphology of Coccidioides at Saboraud's Dextrose Agar
White to tan cotton colony
microscopic morphology of Coccidioides at Lactophenol Cotton Blue
thick walled barrel shaped arthrospores
microscopic morphology of Coccidioides @ Gomori’s methanamine silver
endospores (pathognomonic of coccidioidomycosis)
A.Thrives in Dry Soil w/ High carbon and salt content
B.Semi-Arid Relatively Hot Regions
C.Seen in the Philippines
False about Coccidioides
Pathogenesis of Coccidioides
digging of soil --> aerosol of arthrospores --> inhaled --> become (A) --> (A) produces (B) --> (B) released in lungs
What are (A) and (B), respectively?
victims of Coccidioides are either asymptomatic or with __ infection at primary stage
For pulmonary coccidiomycosis, what is the best specimen to collect?
microscopic morphology of Coccidioides at KOH/Calcofluor white
spherules with endospores
Skin test can be used to diagnose Coccidiomycosis. T or F?
T. exact positive result: redness and swelling
Ohio Valley Fever
These all refer to ___
main difference in mycelial & yeast colonies of Histoplasma
Histoplasma capsulatum , which is of ___ shape, usually inhabits these cells.
habitat of Histoplasma capsulatum
Moist soil due to high nitrogen content supplemented
with bird/bat guano
infective stage of Histoplasma capsulatum
Primary Acute Pulmonary Disease of Histoplasma produces a lesion quite similar to ___ of primary TB
hematogenous spread of Histoplasma produces a lesion quite similar to ___ of progressive TB
lesions present in African Histoplasmosis: enumerate
Mucocutaneous lesions (abscess formation and
Insidious osteolytic lesions in ribs, long bones, and
microscopic exam of Histoplasmosis
Broadly attached buds on thick walled yeast cells: broad
Differentiate Coccidioides fr Histoplasma, in terms of culture.
Histoplasma uses Glucose-Cysteine Blood Agar
Coccidioides uses Blood Agar Slants
also known as __
etiologic agent of Blastomycosis
Blastomyces microscopic morphology @ LPCB
lollipop (very tiny conidia)
Blastomyces microscopic morphology @ Gomori's methanamine silver stain
multinucleated, spherical yeast
A. Dormant: warm, dry season
B. Growth and sporulation: cold, wet season
C. Dwells in soil with low organic matter
Which is false about Blastomyces?
When airborne Blastomyces spores are inhaled by a human, s/he can have what lesions?
granulomatous, suppurated lesions
clin manif of Cutaneous Blastomycosis
painless, raised, verrucous lesions