Flashcards in Cerebral Perfusion and ICP Deck (13)
What is the pathophysiological processes of brain haemorrhage?
Disruption of BBB
Membrane failure, influx of Ca, cellular swelling
Influx of inflammatory mediators
What are the secondary effects of raised ICP?
Decreased cerebral perfusion
What is the Mono-Kellie doctrine?
Fixed volume of brain/CSF/blood is constant
What is the equation for cerebral perfusion pressure?
CPP= MAP - ICP
What is considered to be a normal CPP value?
What is considered to be a normal MAP value?
What is the normal range for ICP?
What are the different forms of herniation syndrome?
Foramen magnum herniation
What area of the brain is involved in subfalcine herniation?
Medial motor cortex
What area of the brain is involved in uncal herniation?
Third cranial nerve
Ipsilateral corticospinal tracts
What area of the brain is involved in formate magnum herniation?
Brain stem centres
How is ICP managed?
Mannitol given intermittently
Taken to ITU for ICP bolt
Head position 30 degrees
Nothing to impede venous drainage
Fully sedated and paralysed