Cerebral Perfusion and ICP Flashcards Preview

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Flashcards in Cerebral Perfusion and ICP Deck (13)
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1

What is the pathophysiological processes of brain haemorrhage?

Disruption of BBB
Membrane failure, influx of Ca, cellular swelling
Influx of inflammatory mediators
Brain swelling
Raised ICP

2

What are the secondary effects of raised ICP?

Herniation syndromes
Decreased cerebral perfusion

3

What is the Mono-Kellie doctrine?

Fixed volume of brain/CSF/blood is constant

4

What is the equation for cerebral perfusion pressure?

CPP= MAP - ICP

5

What is considered to be a normal CPP value?

80mmHg

6

What is considered to be a normal MAP value?

90mmHg

7

What is the normal range for ICP?

5-15mmHg

8

What are the different forms of herniation syndrome?

Subfalcine herniation
Uncal hernation
Foramen magnum herniation

9

What area of the brain is involved in subfalcine herniation?

Medial motor cortex

10

What area of the brain is involved in uncal herniation?

Third cranial nerve
Ipsilateral corticospinal tracts

11

What area of the brain is involved in formate magnum herniation?

Brain stem centres

12

How is ICP managed?

Mannitol given intermittently
Taken to ITU for ICP bolt
Head position 30 degrees
Nothing to impede venous drainage
Fully sedated and paralysed

13

What are the surgical options to reduce ICP?

Craniotomy and evacuation of clot
External ventricular drainage
Decompressive craniectomy