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Flashcards in Testicular Tumours Deck (47)
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1

What is the importance of testicular tumours?

Most common male malignant from 15-44 years

2

What is the ratio of white:black in testicular tumour?

5:1

3

How do testicular tumours present?

Painless testicular lump
Haematospermia
Symptoms of mets or lymph node involvement
Hormonal symptoms

4

What presentation may occur secondary to a testicular tumour?

Hydrocele

5

What symptoms of mets might be present with testicular tumours?

SOB from lung mets

6

What symptoms of lymph node involvement may be present with testicular tumours?

Abdominal mass from para-aortic lymphadenopathy

7

What hormonal symptoms may be present in testicular tumours?

Gynaecomastia
Virilisation

8

What % of patients with testicular tumours have a contralateral tumour?

5%

9

What are the risk factors for testicular tumours?

Undescended testis
Infant hernia
Infertility

10

What % of testicular tumours occur in those with undescended testis?

10%

11

What are the types of testicular tumours?

Germ cell tumours
Non-seminomas
Sex-cord stromal
Lymphoma/leukaemia

12

What % of testicular tumours are germ cell tumours?

95%

13

What are the types of germ cell testicular tumours?

Pure seminomas
Non-seminomas

14

What % of germ cell testicular tumours are pure seminomas?

40%

15

What age do pure seminoma germ cell testicular tumours present?

30-40

16

What tumour markers may be raised in pure seminoma germ cell testicular tumours?

Incrased ßhCG in 15%
Increased placental ALP in some

17

What is true of pure seminoma germ cell testicular tumours, regarding treatment?

They are very radiosensitive

18

What are the types of non-seminoma germ cell testicular tumours?

Mixed
Teratoma
Yolk sac
Choriocarcinoma

19

Where do testicular teratomas arise from?

All 3 germ cell layers

20

How are testicular teratomas different depending on when they present?

They are common and benign in children, but rare and malignant in adults

21

What tumour markers do testicular teratomas secrete?

ßhCG and/or AFP

22

What is true of testicular teratomas, regarding treatment?

Chemosensitive

23

What is the most common testicular tumour in children?

Yolk sac tumour

24

What tumour marker is greatly increased in testicular choriocarcinoma?

ßhCG

25

What are the types of sex-cord stromal testicular tumours?

Leydig cells
Sertoli cells

26

What is true of the prognosis of Leydig cell tumours?

They are mostly benign

27

What might Leydig cell tumours secrete?

Androgens or oestrogens

28

What is true of the prognosis of Sertoli cell tumours?

They are mostly benign

29

What may Sertoli cell tumours secrete?

Oestrogens

30

What is the most common malignant testicular mass >60 years?

Non-hodgkins lymphoma