Innate Response and Th1/Th2 Flashcards Preview

Year 3: CSP & PH > Innate Response and Th1/Th2 > Flashcards

Flashcards in Innate Response and Th1/Th2 Deck (7)
1

What cytokines do macrophages secrete?

TNFa, IL-1, IL-6, IL-8

2

Which cytokine stimulates Th1 cells to be developed

IL-12

3

Which cytokine stimulates Th2 cells to be developed

IL-4

4

Whats the function of Th1 cells?

Secrete IFNg to activate cell-mediated immunity (helps CD8+ T cells and macrophages)

5

Whats the function of Th2 cells?

Secrete IL-4, IL-5 and IL-13 to aid humoral immunity (helps B cells produce antibodies)

6

Which type of T cell is associated with allergy?

Th2; produces IL-4 which leads to IgE production --> allergies

7

Which type of T cell produces more limited (rather than disseminated) disease?

Th1 = limited disease
Th2 = disseminated disease