Flashcards in Innate Response and Th1/Th2 Deck (7)
What cytokines do macrophages secrete?
TNFa, IL-1, IL-6, IL-8
Which cytokine stimulates Th1 cells to be developed
Which cytokine stimulates Th2 cells to be developed
Whats the function of Th1 cells?
Secrete IFNg to activate cell-mediated immunity (helps CD8+ T cells and macrophages)
Whats the function of Th2 cells?
Secrete IL-4, IL-5 and IL-13 to aid humoral immunity (helps B cells produce antibodies)
Which type of T cell is associated with allergy?
Th2; produces IL-4 which leads to IgE production --> allergies