PH: Cancer Epidemiology Flashcards Preview

Year 3: CSP & PH > PH: Cancer Epidemiology > Flashcards

Flashcards in PH: Cancer Epidemiology Deck (9):
1

Why do most cancers develop in epithelial tissues?

Due to a higher rate of mitosis and epithelial cells are exposed to environmental factors.

2

Which cancers have a good prognosis?

Skin (non-melanoma) doesn’t metastasise, those which present with early symptoms, cancers of children and adolescents and cancers that we screen for

3

What (dominant) mutations are associated with breast cancer?

BRCA1/2

4

What (dominant) mutations are associated with retinoblastoma?

Retinoblastoma gene

5

What (dominant) mutations are associated with colorectal cancer?

FAP, HNTCC

6

What (dominant) mutations are associated with stomach and colorectal cancers

Peutz-Jeghers (polyps)

7

What (dominant) mutations are associated with fibrosarcoma?

von Recklinghausen’s

8

What (recessive) mutations are associated with skin cancer?

xeroderma pigmentosum

9

What (recessive) mutations are associated with leukaemia?

ataxia telangiectasia