Pathology - General disorders Flashcards Preview

A - Board Reveiew Misc > Pathology - General disorders > Flashcards

Flashcards in Pathology - General disorders Deck (11)
1

Developmental failure of the 3/4th pharyngeal pouches due to a 22a11 microdeletion

DiGeorge syndrome.

Will lack the thymus.

2

Defective cell mediated and humoral deficiency due to cytokine receptor defects and lack of maturation of B and T cells.

Severe combine immuno deficiency (SCID)

3

Complete lack of immunoglobulin.

typically seen with recurrent infections after 6 months of life.

X-Linked agammaglobinemia.

4

IgA deficiency

Low serum IgA very common.

Increased risk of mucosal infections.

5

Mutation of WASP gene X-linked leading to thrombocytopenia, eczema, and recurrent infections.

Wiskott Aldrich Syndrome

6

What is one who is deficient in C5-C9 at greater risk of?

Neisseria infections.

7

What type of hypersensitivities are seen in SLE?

Type II Cytotoxic and Type III Complement

8

What disorder has a classic finding of small sterile deposits on both sides of the mitral valve known as libman Sacks endocarditis?

SLE

Look for antinuclear antibody and anti-dsDNA antibody.

9

Antihistone Ab is related to SLE in which way?

Highly indicative of drug induced lupus.

think hydralazine, procainamide and isoniazid.

10

destruction of lacrimal and salivary glands.

Sjorgren syndrome.

Characterized by ANA and anti-ribonucleotide antibodies.

11

CREST syndrome

Calcinosis, Raynaud, Esophageal dysmotility, sclerodactly, and telangiectasia.

Characterized by ANA and anti-centromere Ab.

Decks in A - Board Reveiew Misc Class (64):