Flashcards in reproductive pathology Deck (14)
XXY male inactivated X chromosome.
Presents with developmental delay
Short stature with ovarian dysgenesis.
"Hug and kiss from Tina Turner"
Double Y males
Very tall due to nondijunction event.
Associated with severe acne, learning disability, and autism disorders.
46 XX or 47 XXY
Both ovarian and testicular tissue present.
Testosterone levels are high but LH levels are low
This tells you T levels are high regardlss of LH signalling.
Look for testosterone secreting tumor or exogenous steroid use.
Low testosterone levels but high LH levels
What could lead to male or female pseudo hermaphidite?
Females due to excessive androgenic steroids during pregnancy.
Males due to androgen insensitivity syndrome causing the mullerian duct not to form.
what could lead to masculinization of a female?
Aromatase deficiency, the inability to convert estrogen from androgens.
Will have high levels of testosterone and androstenedione.
What would happen if you had a 5 alpha reductase deficiency?
The patient would be unable to convert testosterone to DHT thus there would be high evels of testosterone
What is Kallmann syndrome?
The failure to complete puberty leading to hypogonadotropic hypogonadism.
Defective migration of GnRH cells
What treatment can be given for hypertensive pregnancy?
Alpha methyl Dopa
Look for BP of 140/90
Where are ectopic pregnancies most commonly found
In the ampula of the fallopian tube.
what is the order of most common tumors in the female anatomy
Endometrial > ovarian > cervical