Disorders of Childhood and Adolescence Flashcards Preview

Psychiatry pro +1700 > Disorders of Childhood and Adolescence > Flashcards

Flashcards in Disorders of Childhood and Adolescence Deck (96)
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61

What is the prevalence of bipolar disorder in adolescents?

1%

62

What is a rapid cycler for bipolar adults vs kids?

Adults = 4 times / year
Children = 4 times / day

63

What is the MOA of aripiprazole?

Atypical antipsychotic and mood stabilizer

64

What is the treatment for bipolar disorder?

antipsychotics (mood stabilizers)

65

What are the common side effects with antipsychotics? (3)

-Weight gain
-Tardive dyskinesia
-Increased prolactin

66

What are the two antipsychotics that cause weight gain? Are these typical or atypical antipsychotics?

-Olanzapine
-Clozapine
(both atypical antipsychotics)

67

Where is the weight gain located with antipsychotics?

Centrally

68

What is the major side effect of risperidone? MOA?

Increase prolactin
Atypical antipsychotic

69

What is akathisia? What is this commonly caused by?

Need to move
Bipolar

70

What is the major benefit of quetiapine over other psychotics?

Less EPS

71

What are the two antipsychotics that cause less weight gain?

Aripiprazole
Ziprasidone

72

What is the MOA of antipsychotics?

Reduce the dopamine in mesolimbic area of the brain

73

What are the typical antipsychotics? (4)

Chlorpromazine
Thioridazine
Fluphenazine
Haloperidol

74

What are the atypical antipsychotics? (6)

Clozapine (Clozaril)
Olanzapine (Zyprexa)
Risperidone (Risperdal)
Aripiprazole (Abilify)
Quetiapine (Seroquel)
Ziprasidone (Geodon)

("Old Quietly Risper from A to Z")

75

What are the major side effects of antipsychotics? (4)

-Sedation
-Akathisia
-Parkinsonian s/sx
-Orthostatic Hypotension

76

What is the treatment for dystonia use with antipsychotics?

Antihistamine

77

What is neuroleptics malignant syndrome? S/sx? Lab change?

-Adverse reaction to antipsychotics, and dopamine blockade
-presenting with fever, autonomic instability, and delirium.
-Increased CK

78

What is the treatment for neuroleptic malignant syndrome?

-Stop med
-Treat hyperthermia
-Dantrolene for muscle rigidity, and bromocriptine

79

What labs must be monitored with Li use? (3)

-TSH (hypothyroidism)
-Cr
-CBC

80

What must be monitored with Depakote (valproic acid) use? (3)

-LFTs
-CBC
-pCO

81

What is the major side effect of lamotrigine?

Steve-Johnson syndrome

82

What are the major side effect of tegretol (carbamazepine)?

Aplastic anemia

83

What is the major issue with Li?

Chronic renal insufficiency, and narrow therapeutic index

84

What are the only two drugs that have been proven to decrease suicidality?

Clozapine
Li

85

What are the skin side effects of Li?

Acne

86

What are the endocrine problems with Li?

Hypothyroidism

87

What happens to the tremor with Li?

Increase from fine to coarse as increased dose

88

What is the major cardiac issue with Li?

Cardiac arrhythmia

89

What is the only OTC analgesic that is appropriate with Li intake?

Acetaminophen

90

What is the major adverse reaction to (clozapine)?

Agranulocytosis