Flashcards in Neurocognitive Disorders Deck (87)
What are the diagnostic criteria / domains for neurocognitive decline? (6)
-Learning and memory
What is the difference between major and minor cognitive decline?
Major = significant impairment
Minor = modest decline
Dementia is unusual to see prior to what age?
True or false: very few cases of dementia are reversible
What is the most common cause of dementia?
What areas of the brain (lobes) are affected with AD?
Parietal and temporal lobes
True or false: dementia is a normal part of aging
What are the genes that are associated with AD?
Presenilin 1 and 2
amyloid precursor protein
What is the gene that is associated with early onset AD?
What is the gene that is protective against AD?
True or false: early onset AD has a strong genetic component
What is the natural h/o AD?
Gradual onset and progression
What are the two major questions that are used to screen for AD?
-lost in a well known area
-Cannot pay bills
What is the neurotransmitter that is changed with AD?
What are the histological findings of AD?
What is the average survival rate of AD?
What is the function of the Tau proteins?
Maintaining neuronal function (microtubule associated proteins)
What areas of the brain are particularly affected with AD?
What is Binswanger's disease? Which part of the brain is usually affected?
Multi Infarct dementia that is usually subcortical, but progresses to cortical dementia
What disease usually coexists with AD?
What is the second most common type of dementia?
What are the psychosis s/sx of lewy body dementia?
-Visual hallucinations/ delusions
What are the s/sx of PD? (TRAP)
What is the treatment for lewy body disease? What should never be used?
Never use antipsychotics
What is Pick's disease?
Frontotemporal dementia--selective atrophy that involved the temporal and/or frontal lobes of the brain
When does frontotemporal dementia usually present, relative to AD?
50s as opposed to 70s for AD
What are the first s/sx of frontotemporal dementia?
Disinhibition and language problems
When do s/sx of CTE usually present?
8-10 years following repeated concussions
What are the usual s/sx of CTE?
-Memory loss, poor judgement