MDD and bipolar I Flashcards

1
Q

What are the top two conditions that PCPs see?

A
  1. HTN

2. Depression

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2
Q

What fraction of adults have depression?

A

1/10

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3
Q

What is dysthymia?

A

a mood disorder consisting of the same cognitive and physical problems as in depression, with less severe but longer-lasting symptoms

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4
Q

1st degree relatives of depressive patients are how many times more likely to have depression?

A

1.5-3x more likely

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5
Q

True or false: first degree relatives of those with depression have an increased risk of alcohol use

A

True

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6
Q

Children of individuals with MDD have an increased risk of what other diseases?

A

Anxiety

AD(H)D

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7
Q

What are the labs that are diagnostic for depression?

A

There are none

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8
Q

What is the pathophysiology of depression?

A
  • Dysregulation of several neurotransmitter systems

- Dysregulation of cerebral blood flow

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9
Q

True or false: all patients with depression have some sort of identifiable pathophysiology causing their depression

A

False

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10
Q

What are the diagnostic criteria for depression? (9)

A
  • depressed mood
  • Anhedonia
  • Change in appetite or weight
  • change in sleeping habits
  • Psychomotor agitation or retardation
  • Fatigue
  • Feelings of worthlessness or guilt
  • Diminished ability to concentrate
  • Recurrent thoughts of death

(FC GRAMPAS)

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11
Q

How long do s/sx of MDD have to last to be considered MDD? How many s/sx are needed?

A

For at least 2 weeks, 5+ symptoms, at least one of which is loss of interest/pleasure in ALL things

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12
Q

Women are how many times more likely to have a depressive episode as compared to men?

A

2x

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13
Q

True or false: the increased risk for depression in women is true for young girls compared to boys

A

False

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14
Q

What is the average age of onset for depression?

A

mid 20s

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15
Q

True or false: unlike anxiety disorders, MDD tends to be episodic

A

True

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16
Q

True or false: most of the time, depression is self limiting

A

True

17
Q

What percent of individuals who meet criteria for MDD still meet the criteria a year later?

A

40%

18
Q

What percent of individuals who have an episode of MDD never have another?

A

40%

19
Q

True or false: usually the first/second episode of MDD is preceded by a psychosocial stressor

A

True

20
Q

What is the dysthymia that occurs with depression?

A

Loss of interest in most things, not just one thing

21
Q

How can you differentiate grief from depression?

A

Grief is largely transient, variable, and has a cause, while depression is a pervasive mood disruption that does not vary

22
Q

True or false: it is not uncommon to have some psychotic s/sx with grief reactions

A

True

23
Q

What is adjustment disorder with depressed mood?

A

Persistent depression 2/2 significant life change

24
Q

What is the right way to view depression in patients who are well off?

A

Risk factors

25
Q

What is dysthymia (Persistent depressive disorder)?

A

Chronic, low grade depression over 2 years time that may not meet full criteria for MDD

26
Q

What are two things that should be r/o with all MDD, but especially those who are hospitalized?

A
  • Mood disorder 2/2 general medical condition

- Substance-induced mood disorder

27
Q

What should always be asked prior to asking about mood?

A

Mental status

28
Q

What are the five diagnostic modifiers with depression?

A
  • mild
  • moderate
  • severe
  • part remission
  • full remission
29
Q

What are the mixed features modifier of MDD?

A

Criteria are met for both a depressive episode and a manic episode simultaneously for at least a week

30
Q

What is disruptive mood dysregulation disorder?

A

a psychiatric disorder, characterized by persistently irritable or angry mood with recurrent, severe temper outbursts

31
Q

Can you have manic s/sx and still have MDD?

A

No

32
Q

What is unspecified depressive disorder?

A

Had a clinically significant depressive event, but not enough to meet criteria

33
Q

What should always be r/o with MDD s/sx?

A

Substance abuse

34
Q

What should always be assessed for prior to dispensing antidepressants?

A

Bipolar disorder

35
Q

What is the strongest indicator for predicting recurrence of depression?

A

Residual symptoms