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Flashcards in MDD and bipolar I Deck (35):
1

What are the top two conditions that PCPs see?

1. HTN
2. Depression

2

What fraction of adults have depression?

1/10

3

What is dysthymia?

a mood disorder consisting of the same cognitive and physical problems as in depression, with less severe but longer-lasting symptoms

4

1st degree relatives of depressive patients are how many times more likely to have depression?

1.5-3x more likely

5

True or false: first degree relatives of those with depression have an increased risk of alcohol use

True

6

Children of individuals with MDD have an increased risk of what other diseases?

Anxiety
AD(H)D

7

What are the labs that are diagnostic for depression?

There are none

8

What is the pathophysiology of depression?

-Dysregulation of several neurotransmitter systems
-Dysregulation of cerebral blood flow

9

True or false: all patients with depression have some sort of identifiable pathophysiology causing their depression

False

10

What are the diagnostic criteria for depression? (9)

-depressed mood
-Anhedonia
-Change in appetite or weight
-change in sleeping habits
-Psychomotor agitation or retardation
-Fatigue
-Feelings of worthlessness or guilt
-Diminished ability to concentrate
-Recurrent thoughts of death

(FC GRAMPAS)

11

How long do s/sx of MDD have to last to be considered MDD? How many s/sx are needed?

For at least 2 weeks, 5+ symptoms, at least one of which is loss of interest/pleasure in ALL things

12

Women are how many times more likely to have a depressive episode as compared to men?

2x

13

True or false: the increased risk for depression in women is true for young girls compared to boys

False

14

What is the average age of onset for depression?

mid 20s

15

True or false: unlike anxiety disorders, MDD tends to be episodic

True

16

True or false: most of the time, depression is self limiting

True

17

What percent of individuals who meet criteria for MDD still meet the criteria a year later?

40%

18

What percent of individuals who have an episode of MDD never have another?

40%

19

True or false: usually the first/second episode of MDD is preceded by a psychosocial stressor

True

20

What is the dysthymia that occurs with depression?

Loss of interest in most things, not just one thing

21

How can you differentiate grief from depression?

Grief is largely transient, variable, and has a cause, while depression is a pervasive mood disruption that does not vary

22

True or false: it is not uncommon to have some psychotic s/sx with grief reactions

True

23

What is adjustment disorder with depressed mood?

Persistent depression 2/2 significant life change

24

What is the right way to view depression in patients who are well off?

Risk factors

25

What is dysthymia (Persistent depressive disorder)?

Chronic, low grade depression over 2 years time that may not meet full criteria for MDD

26

What are two things that should be r/o with all MDD, but especially those who are hospitalized?

-Mood disorder 2/2 general medical condition
-Substance-induced mood disorder

27

What should always be asked prior to asking about mood?

Mental status

28

What are the five diagnostic modifiers with depression?

-mild
-moderate
-severe
-part remission
-full remission

29

What are the mixed features modifier of MDD?

Criteria are met for both a depressive episode and a manic episode simultaneously for at least a week

30

What is disruptive mood dysregulation disorder?

a psychiatric disorder, characterized by persistently irritable or angry mood with recurrent, severe temper outbursts

31

Can you have manic s/sx and still have MDD?

No

32

What is unspecified depressive disorder?

Had a clinically significant depressive event, but not enough to meet criteria

33

What should always be r/o with MDD s/sx?

Substance abuse

34

What should always be assessed for prior to dispensing antidepressants?

Bipolar disorder

35

What is the strongest indicator for predicting recurrence of depression?

Residual symptoms