Substance Abuse II Flashcards Preview

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Flashcards in Substance Abuse II Deck (83):
1

What are the criteria for caffeine use disorder?

No such thing

2

What is considered "high dose" caffeine?

250 mg

3

What are the criteria for caffeine intoxication? (non -obvious)? How many are needed?

-Flushed face

5

4

What are the criteria for caffeine withdrawal? How many within a 24 hours timeframe are needed to diganose?

At least 3 within 24 hours:
-HA
-Fatigue
-Dysphoric
-Flu-like s/sx
-Difficulty concentring

5

What is the major issue with Li and Caffeine use?

Diuretic aspect of caffeine may alter [Li]

6

What is the most widely used illicit substance?

Marijunana

7

What is the age range that has the highest marijuana use?

18-29 years

8

True or false: regular users of marijuana had concurrent metal disorders

True

9

True or false: most individuals who use cannabis report that they use it solely for pleasure

False--cope with mood, sleep, pain etc

10

What are the four criteria for marijuana intoxication? How many are needed? Within what time frame?

2 within 2 hours:
-Conjunctival injection
-Increased appetite
-Dry mouth
-Tachycardia

11

What is "K2?

Synthetic cannabinoid--sprayed onto herbal/plant matter

12

What are the major effects of synthetic cannabinoid?

-Anxious
-Irritable
-Cognitive impairment
-Psychosis

13

How reliable are tox screens for K2?

Not very

14

What are the physical effects of K2?

Conjunctival injection

15

What are the s/sx of cannabis withdrawal?

-Sleep difficulty
-Anxiety
-Decreased appetite

16

What are the major phencyclidines?

-PCP
-Ketamine

17

What are the s/sx of phencyclidine (PCP) use? (5)

-Dissociative symptoms
-Nystagmus
-HTN
-Violent behavior
-Analgesia

18

What are the complications that can result from phencyclidine use?

-Cognitive deficits
-Szs
-Intracranial hemorrhage

19

What is MDMA?

Ecstasy

20

What are the eye findings with phencyclidine use?

-Pupillary dilation
-Nystagmus

21

What are the muscle findings of phencyclidine?

-Rigidity
-Ataxia
-Dysarthria

22

What are the CV effects of Phencyclidine intoxication?

-Tachycardia
-HTN

23

How mayn diagnostic criteria are needed, and in what timeframe, for phencyclidine intoxication?

Within 1 hour, at least 2

24

What are the ocular s/sx of hallucinogenic intoxication?

Dilation
Blurred vision

25

True or false: there is no withdrawal with inhalant use

True

26

What are the general features of inhalant intoxication?

-Belligerence
-lethargy
-Impaired judgement

27

What are the the ocular findings of inhalant use?

-Nystagmus
-Blurred vision
-Diplopia

28

What are the motor findings of inhalant intoxication? (4)

-Incoordination
-Psychomotor retardation
-Tremor
-Generalized weakness

29

What is the common cause of death with inhalant use?

Cardiac arrhythmias

30

What is the general MOA of opioids?

Mu-opioid receptor agonist

31

What happens after the euphoric-Perceptual motor phase with opioid use?

Apathy and dysphoria

32

What happens to motor function with opioid intoxication?

Agitation or retardation

33

What are the diagnostic criteria for opioid intoxication? (4)

Pupillary constriction + 1 or more of:
-Slurred speech
-Drowsiness
-Impairment in attention or memory

34

How many criteria are needed to diagnose opioid withdrawal? In what timeframe?

3 or more within minutes to days

35

What are the ocular findings with opioid withdrawal?

Pupillary dilation

36

What are the general s/sx of opioid withdrawal?

-Dysphoria
-N/v
-myalgias

37

What are the ANS findings of opioid withdrawal? (3)

-Lacrimation / rhinorrhea
-Piloerection
-Diaphoresis

38

What are the GI findings of opioid withdrawal?

Diarrhea

39

What is the name of the diagnostic algorithm used to diagnose opioid withdrawal?

COWS

40

What are the three major medication used in opioid withdrawal?

-Methadone
-Buprenorphine
-Naltrexone

41

What is the MOA of methadone?

Long acting synthetic opioid agonist

42

What s the MOA of buprenorphine?

Synthetic partial agonist of opioid receptors

43

What is the MOA of naltrexone?

opioid antagonist

44

Why give buprenorphine and naloxone as a combination?

Naloxone is not enterically absorbed, so if used PO, then the buprenorphine will give only a small high. If injected, then naloxone will cause withdrawal symptoms

45

True or false: craving is not typical with Sedatives / hypnotics / Anxiolytic use

False

46

Sedatives / hypnotics / Anxiolytic use appears very similar to what other substance?

EtOH

47

True or false: if you experience withdrawal from prescribed use of Sedatives / hypnotics / Anxiolytic, then you are diagnosed with use disorder

False

48

What are the s/sx of Sedatives / hypnotics / Anxiolytic intoxication?

-Impaired judgement
-Mood lability
-Inappropriate or sexual behavior

49

What are the motor findings of Sedatives / hypnotics / Anxiolytic use?

-Slurred speech
-Incoordination
-Unsteady gait

50

What are the ocular findings of Sedatives / hypnotics / Anxiolytic intoxication?

Nystagmus

51

How many diagnostic criteria are needed for Sedatives / hypnotics / Anxiolytic intoxication?

1 or more

52

What are the cognitive effects of Sedatives / hypnotics / Anxiolytic intoxication?

-Impairment
-Stupor/coma

53

What is the reversal agent for benzos? MOA?

-Flumazenil
-GABA antagonist

54

How many diagnostic criteria are needed to diagnose anxiolytic/sedative withdrawal? In what timeframe?

2 or more within hour to days

55

What are the nervous system withdrawal symptoms of anxiolytic withdrawal?

-ANS hyperactivity
-Psychomotor agitation
-Hallucinations
-Seizures

56

True or false: reality testing is intact with withdrawal from anxiolytic use

True

57

What are the results of long term use of stimulants? (4)

-Chaotic behavior
-Social isolation
-Sexual dysfunction
-Aggressive behavior

58

What are the non-obvious s/sx of stimulant use intoxication?

-Stereotyped and repetitive behavior
-Tension and anxiety

59

What are the pupillary findings of stimulant use?

Dilation

60

What are the CV criteria for stimulant intoxication?

-Tachycardia or bradycardia
-HTN or hypotension
-Cardiac arrhythmias

61

What are the psychomotor criteria for stimulant intoxication?

Retardation or agitation

62

What are the GI criteria for stimulant intoxication?

-n/v
-Weight loss

63

NDMA is structurally similar to what other illicit drug?

Methamphetamine

64

What are the CNS complications from cocaine use?

-SAH
-HA
-CVA
-Szs

65

What is the major muscular complication from cocaine use?

Rhabdomyolysis

66

What are the GI complications from cocaine use?

Intestinal ischemia
-gangrene

67

What are the OB complications from cocaine use?

-Abruptio placenta
-Spontaneous abortion
-Premature labor
-Perinatal mortality

68

True or false: cocaine can cause DKA

True

69

What are the diagnostic criteria for stimulant withdrawal (1 + 5)

Dysphoric mood +
-Fatigue
-Vivid dreams
-Sleep changes
-Increased appetite
-Psychomotor retardation

70

True or false: there is NO tobacco intoxication

True

71

What are the criteria for tobacco use disorder?

Daily use

72

What are some of the intranasal complications from cocaine use?

-Anosmia
-Necrosis and perforation of the nasal septum

73

What is the timeframe and symptoms amount needed to diagnose tobacco withdrawal?

Within 24 hours
4 or more

74

What happens to appetite with tobacco withdrawal?

INcreased

75

What happens to mood with tobacco withdrawal?

Depression / dysphoria

76

What is the first step in the treatment of withdrawal? What are the limitations of this?

Detox
-Does not address social/psych concerns

77

What is the hopsital model for short term residential rehab?

- 3-6 week hospital inpt tratment
-outpatient care
-self help group

78

What is the long term residental model for rehab?

-6-12 months
-Resocialization
-Struturalization

79

What are the focuses of outpatient rehab programs?

-group counseling
-Intensive day treatment

80

What are the focuses of individual rehab counseling?

-Areas of impaired functioning
-Short term behavioral goals

81

What is the cost for alcoholics anonymous?

Free

82

What are the three keys to alcoholics anonymous?

-Acceptance
-Surrender-
-12 step program

83

What is the role of Gas chromatography and mass spec in drug testing?

Confirmatory