Flashcards in MDD and bipolar II Deck (54)
What is the role of psychotherapy and psychopharmacology?
Complementary--psychopharmacology outcomes are largely improved with psychotherapy
What is transcranial magnetic stimulation?
A noninvasive method used to stimulate small regions of the brain. During a TMS procedure, a magnetic field generator, or "coil", is placed near the head of the person receiving the treatment. The coil produces small electric currents in the region of the brain just under the coil via electromagnetic induction. The coil is connected to a pulse generator, or stimulator, that delivers electric current to the coil
What is the role of ketamine in the treatment for depression? What is the MOA?
NMDA receptor antagonist
What is the role of exercise in MDD?
Treatment, but not cure
What is the black box warning for antidepressants?
Increase risk for suicidal ideation if young. Usually occurs in the first 2 weeks
True or false: improvements in mood can be seen in the first week of antidepressant therapy
True, but smaller than full effect
What is the MOA of duloxetine?
What is the difference in response vs remission in the treatment of MDD?
-Response = 50% reduction
-Remission = 100%
Should you dose antidepressants according to severity of symptoms?
What are the major TCAs?
What is the MOA of venlafaxine?
What is the MOA of desvenlafaxine?
What is the MOA of levomilnacipran?
What is the MOA of fluoxetine?
What is the MOA of fluvoxamine?
What is the MOA of paroxetine?
What is the MOA of sertraline?
Which of the SSRIs can cause QTc prolongation?
Citalopram and escitalopram
What is the MOA of SNRIs?
Increase 5HT and NE
True or false: there is no such thing as a stronger or weaker antidepressant
What is the MOA of vilazodone?
SSRI with 5HT1 binding properties
What is the MOA of vortioxetine?
SSRI with multiple serotonin properties
What is the effect of vilazodone and vortioxetine on weight?
What is the MOA of bupropion?
NE and dopamine reuptake inhibitor
What is the MOA of mirtazapine? What is it known for?
Alpha 2 blocker and serotonin blocker
Weight gain (good in cachectic patients)
What is the MOA of trazodone?
Inhibition of 5HT2A receptors. Human and animal studies have demonstrated that inhibition of this receptor is associated with antianxiety, antipsychotic and antidepressant effects.
What is the MOA of Quetiapine?
What is methylphenidate?
What is dextroamphetamine?