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Flashcards in Cystic Fibrosis 2 Deck (27)
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1

What are further issues with CF?

Fertility

Transplantation

2

What effect does CF have on the sexual function of men and woman?

No effect

3

What may CF do to puberty?

Cause it to occur later

4

How does CF affect fertility in men?

>95% are infertile

5

How does CF affect fertility in females?

They are fertile but poor nutrition may change that

6

What options are available for infertile males?

Adoption

Artificial insemination with donor sperm

Intra-cytoplasmic sperm injection (ICSI)

7

What is the success rate of artificial insemination with a donor sperm?

60-70% success rate

8

What is the waiting list for intra-cytoplasmic sperm injection (ICSI)?

4 months

9

What is the success rate of intra-cytoplasmic sperm injection (ICSI)?

25-30%

10

What does ICSI stand up for?

Inta-cytoplasmic sperm injection

11

How many attemps of ICSI is on the NHS?

3

12

What is the cost of ICSI treatment?

£3000-4000

13

What are the female fertility issues?

Major decisions (ethically and clinically)

Careful planning essential

Screening of partner

Counselling regarding long term impact of condition on family

Good communication with CF team

Optimum health (lung function and weight)

14

What is the main risk for mothers with CF?

Baby is born premature, where the mothers can do badly

15

What should be known about lung transplantation?

Last resort treatment

Not a miracle cure

16

Where are lung transplants for grampian people done?

Freeman Hospital, Newcastle

17

What kind of lung transplant is perfomed?

Double lung transplant

18

When are patients bad enough for a lung transplant?

FEV1 < 30% predicted

Lots of weight loss

Hypoxia at rest/desaturation on exercise

Hypercapnia

Recurrent worsening sepsis

Worsening quality of life

19

Where are patients for a lung transplant often seen first?

Satellite clinic in Edinburgh

20

What happens during the formal assessment for a lung transplant?

3 or 4 day admission

Must bring carer

Seen by multidiscipline team

Clinical investigations

Two way information sharing process

Multi-disciplinary meeting where the decision is made

21

What are potential outcomes of the initial assessment?

Active list

Passive list

Too well

Decision not to go onto list (by patient)

Decision not to go onto list (by team)

Too ill

22

What are 3 questions that you need to ask before doing a lung transplant?

Is the condition bad enough?

Is the rest of the body good enough?

Does the patient want this (prepared to take the gamble)?

23

What are absolute conta-indications to transplant?

Other organ failure

Malignancy within 5 years

Significant peripheral vascular disease

Drug, nicotinne, alcohol dependency

Active systemic infection

Microbiological issues

24

What are relative conta-indications for transplant?

Other organ dysfunction

Non-compliance

Steroids >20mg daily

Absence of recognised social support

Osteoporosis

Low BMI

Surgical risks (previous thoracic surgery)

25

What are some psychological issues for a lung transplant?

Hope

Fear

Guilt/conflict

Stress

26

What percentage of people who get double lung transplants survive 5 years?

61%

27

What percentage of people who get double lung transplants survive 10 years?

48%