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Flashcards in Obesity I Deck (36)
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1

What is the technical definition of obesity?

Excess body fat

BMI >30

2

True or false: OA is a risk factor of obesity

True

3

True or false: gallstones and renal stones are risk factors of obesity

not renal stones, but gall stones yes.

4

True or false: GYN abnormalities are risk factors of obesity

True

5

How large a role are genetics in obesity?

Small

6

How does polycystic ovarian syndrome lead to obesity?

Too much insulin is being produced, and does not function normally

7

How does hypothyroidism lead to obesity?

Decrease in thyroid hormone

8

How does Cushing's syndrome lead to obesity?

Adrenal glands overproduce cortisol

9

What are the meds that lead to weight gain? (5)

Antipsychotics
Antidepressants
DM meds
Antiepileptic
Glucocorticoids

10

What is the adaptive viewpoint of fat and evolution?

Accumulation of fat was advantageous

11

What are "thrifty genes"?

Theoretical genes that caused increased fat deposition, due to common famine

12

What is the maladaptive viewpoint of obesity?

Obesity has never been advantageous--some do not have brown adipose tissue

13

What is the neutral viewpoint of obesity?

Obesity never advantageous.

Many genes involved in weight regulation

14

What is the set point theory?

Upper and lower points exist, but upper point increased

15

What are the three key players in energy homeostasis?

Brain
GI tract
Adipose tissue

16

What are the 5 major chemical players in appetite?

Leptin
Ghrelin
GLP-1
PYY
CCK

17

What is the prandial state?

Food recently taken in, is in the blood

18

What is the postabsorptive state?

Absence of calories entering the circulation from the GI tract--rely on stores

19

What is the role of CCK?

Peptide hormone produced by the small intestines in response to feedings, causing pancreas to excrete enzymes

20

What is the role of the PYY hormone?

Insulin peptide hormone released by pancreas in response to elevated levels of blood glucose

21

What is the role of GLP-1? (3)

-Increases insulin secretion/sensitivity
-Decreases glucagon
-Inhibits acid secretion and gastric emptying

22

What is the role of leptin?

Peptide hormone released by adipose tissue to hypothalamus to signal satiety

23

What is a genetic disease where leptin resistance is common?

Prader-Willi syndrome

24

What is the role of ghrelin?

Peptide hormone produced by stomach lining, goes to CNS, increases hunger

25

Physical hunger or emotional hunger: hunger that develops suddenly

Emotional

26

Physical hunger or emotional hunger: specific food craving

Emotional

27

Physical hunger or emotional hunger: above the neck hunger cues

Emotional

28

Physical hunger or emotional hunger: deliberate choices while eating

Physical hunger

29

Physical hunger or emotional hunger: results in overeating

EMotional

30

Physical hunger or emotional hunger: results in feelings of nourishment and satisfaction

Physical