MEH - Energy Storage (Glycogen And Fat) Flashcards Preview

CJ: UoL Medicine Semester Two (ESA2) > MEH - Energy Storage (Glycogen And Fat) > Flashcards

Flashcards in MEH - Energy Storage (Glycogen And Fat) Deck (33)
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31

Where does fatty acid synthesis mainly occur?

In the liver

32

How does lipgloss occur?

Hormone sensitive lipase (stimulated by gluconeogenesis/adrenaline, inhibited by insulin) causes break down of triacylglycerol into glycerol and free fatty acids in the blood

33

Outline fatty acid synthesis

- Pyruvate enters mitochondria and forms acetyl-CoA & OAA which then condense to form citrate
- Citrate enters cytoplasm and cleaved back to Acetyl-CoA & OAA
- Acetyl-CoA carboxylase (key regulator) produces
malonyl-CoA from Acetyl-CoA.
- Fatty acid synthase complex builds fatty acids by sequential addition of 2 carbon units provided by malonyl-CoA.

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