Antimicrobial Chemotherapy 2 Flashcards Preview

Principles of Disease > Antimicrobial Chemotherapy 2 > Flashcards

Flashcards in Antimicrobial Chemotherapy 2 Deck (69)
Loading flashcards...
1

What are some commonly used B-lactams (penicillins)?

Benzyl penicillin

Amoxicillin, ampicillin

Co-amoxicaly

Flucloxacillin

Piperacillin

Imipenem, meropenum

2

What does benzyl penicillin act against?

Gram positive bacteria

3

What does amoxicillin and ampicillin act against?

Gram negative bacteria

4

What does co-amoxicaly act against?

B-lactamase producing coliforms

5

What is flucloxacillin the best treatment for?

Staphyloccocal infection

6

What does piperacillin treat?

Extended gram negative coverage

7

What does imipenem and meropenem treat?

Most bacteria, including anaerobes

8

What is a class of B-lactams other than penicillin?

Cephalosporins

9

How does the activity of cephalosporins change against gram negative and positve bacteria through the generations?

Activity against gram negative bacteria increases

Activity against gram positive bacteria decreases

10

What are the 3 generations of cephalosporins?

1) Cephradine

2) Cefluoxime

3) Ceftrixone

11

What are some commonly used agents other than B-lactams?

Aminoglycosides

Glycopeptides

Macrolides

Quinolones

12

How are aminoglycosides administered?

Only parenterally

13

What are aminoglycosides useful against?

Gram negative bacteria

14

What gram positive bacteria is sensitive to aminoglycosides?

Only staphylococci

15

What is an example of an aminoglycoside?

Gentamicin

16

How are glycopeptides administered?

Parenteral use only

17

What are glycopeptides active against?

Gram positive bacteria (anaerobic and aerobic)

18

What are examples of glycopeptides?

Vancomycin

Teicoplanin

19

What are macrolides mainly active against?

Gram positive bacteria

20

When are macrolides often used?

As an alternative to penicillin for people who are allergic

21

What are examples of macrolides?

Clarithromycin

Erythromycin

Azithromycin

22

What are quinolones active against?

Nearly all gram negative bacteria

23

What are some miscellaneous commonly used agents?

Metranidazole

Fusidic acid

Co-trimoxazole

Tetracyclines

Clindamycin

24

What is metronidazole used against?

Anaerobes, both gram positive and negative

25

What is fusidic acid used against?

Staphyloccocus

26

What is co-trimoxazole?

A combination of trimethoprim and sulphamethoxazole

27

What kinds of infection are tetracyclines useful for?

Some genetial tract and respiratory tract infections

28

What is clindamycin useful against?

Gram positive and anaerobes

29

What are some commonly used new agents?

Linezolid

Daptomycin

30

What is linezolid used against?

MRSA