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Flashcards in Tumour Pathology 1 Deck (35)
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1

What is a tumour?

Abnormal growing mass of tissue

2

What are the properties of the growth of a tumour?

Growth is uncoordinated with that of surrounding normal tissue

Growth continues after the removal of any stimulis which may have caused the tumour

Irreversible change

3

What are the two types of tumours?

Beneign

Malignant (also known as a cancer)

4

What is a fundamental property of cancer?

Its ability to invade into adjacent tissues and to metastasis (spread) and grow at other sites within the body

5

What is metastasis?

Spreading of a tumour

6

What is cancer caused by (vaugly)?

Genetics

Environment

7

What are the top 5 cancers in men?

1) Prostate

2) Lung

3) Colon

4) Kidney

5) Melanoma

8

What are the top 5 cancers in woman?

1) Breast

2) Lung

3) Colon

4) Uterus

5) Melanoma

9

What are the top 5 cancers in both men and woman?

10

What is the 5 year survival rate like for cancers?

11

Why is it important to classify tumours?

Understanding tumour behaviour

Determining the prognosis (outcome) and selecting therapy

12

What is the classification of a tumour based on?

Tissue of origin

Benign or malignant

13

What are some origin tissues for tumours?

Epithelium

Connective tissue

Blood cells

Lymphoid tissue

Melanocytes

Neural tissues

Germ cells

14

What are benign and maligant glandular epithelium tumours called?

Benign are called adenoma

Malignant is called adeno-carcinoma

15

What are benign and malignant squamous tumours called?

Benign are called squamous papilloma

Malignant are called squamous carcinoma

16

What are some connective tissues that a tumour can arise in?

Bone

Fat

Fibrous tissue

17

What are beneign and maligant bone tumours called?

Benign are called osteoma

Malignant are called osteo-sarcoma

18

What are benign and malignant fat tumours called?

Benign are called lipoma

Malignant are called lip-sarcoma

19

What are beneign and malignant fibrous tissue tumours called?

Benign are called fibroma

Malignant are called fibro-sarcoma

20

What are benign and malignant blood tumours called?

There are no benign blood tumours

Malignant blood tumours are called leukaemia

21

What are benign and malignant lymphoid tissue tumours called?

There are no benign lymphoid tissue tumours

Malignant are called lymphoma

22

What are benign and malignant melanocyte tumours are?

Benign are called naevus

Malignant are called melanoma

23

What are neural tissue tumours called?

Astrocytoma (CNS)

Schwannoma (PNS)

24

What are germ cell tumours called?

Teratomas

25

What kind of tumour are testicular normally?

Malignant

26

What kind of tumour are ovaries normally?

Benign

27

What are teratomas usually composed of?

Various tissues

28

What are features in both benign and malignant tumours?

Growth pattern

Presence of capsule

Invasion

Presence of metastasis

Differentiation

Appearance of tumour cell

Function

Behaviour

29

What are features of benign tumours?

Non-invasive growth pattern

Usually encapsulated

No evidence of invastion

No metastasis

Cells similar to normal

Well differentiated

Function similar to normal tissue

Rarely cause death

30

What are features of malignant tumours?

Invasive growth pattern

No capsule or capsule breached by tumour cell

Cells abnormal

Poorly differentiated

Loss of normal function

Evidence of spread of cancer

Frequently cause death